Manifestation of malaria in Mangaluru, southern India

Malaria Journal
Prabhanjan P GaiDamodara Shenoy

Abstract

Severe and fatal vivax malaria is increasingly reported from India. In Mangaluru, southern India, malaria is focused in urban areas and associated with importation by migrant workers. In Wenlock Hospital, the largest governmental hospital, the clinical, parasitological and biochemical characteristics of malaria patients were assessed. During the peak malaria season in 2015 (June to December), outpatients were interviewed and clinically assessed. Malaria was ascertained by microscopy and PCR assays, concentrations of haemoglobin, creatinine and bilirubin, as well as thrombocyte count, were determined, and severe malaria was defined according to WHO criteria. Among 909 malaria patients, the vast majority was male (93%), adult (median, 26 years) and of low socio-economic status. Roughly half of them were migrants from beyond the local Karnataka state, mostly from northern and northeastern states. Vivax malaria (69.6%) predominated over mixed Plasmodium vivax-Plasmodium falciparum infection (21.3%) and falciparum malaria (9.0%). The geometric mean parasite density was 3412/µL. As compared to vivax malaria, patients with falciparum malaria had higher parasite density and more frequently showed impaired general condition, affected co...Continue Reading

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Citations

Nov 7, 2018·The American Journal of Tropical Medicine and Hygiene·Jakob WedamFrank P Mockenhaupt
Jun 21, 2019·The American Journal of Tropical Medicine and Hygiene·Costanza TacoliFrank P Mockenhaupt
Mar 4, 2020·The American Journal of Tropical Medicine and Hygiene·Welmoed van LoonFrank P Mockenhaupt
Sep 26, 2019·Malaria Journal·Prabhanjan P GaiFrank P Mockenhaupt
Nov 1, 2020·Annals of Clinical Microbiology and Antimicrobials·Monika MatlaniVineeta Singh
Apr 9, 2021·The Journal of Infection·Loick P Kojom FokoVineeta Singh

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Methods Mentioned

BETA
PCR

Software Mentioned

SPSS
Statview

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