Manipulation and Deposition of Complex, Functional Block Copolymer Nanostructures Using Optical Tweezers

ACS Nano
Oliver E C GouldIan Manners

Abstract

Block copolymer self-assembly has enabled the creation of a range of solution-phase nanostructures with applications from optoelectronics and biomedicine to catalysis. However, to incorporate such materials into devices a method that facilitates their precise manipulation and deposition is desirable. Herein we describe how optical tweezers can be used to trap, manipulate, and pattern individual cylindrical micelles and larger hybrid micellar materials. Through the combination of TIRF imaging and optical trapping we can precisely control the three-dimensional motion of individual cylindrical block copolymer micelles in solution, enabling the creation of customizable arrays. We also demonstrate that dynamic holographic assembly enables the creation of ordered customizable arrays of complex hybrid block copolymer structures. By creating a program which automatically identifies, traps, and then deposits multiple assemblies simultaneously we have been able to dramatically speed up this normally slow process, enabling the fabrication of arrays of hybrid structures containing hundreds of assemblies in minutes rather than hours.

References

Jan 24, 2006·Nature Materials·Peter J PauzauskieJan Liphardt
Apr 3, 2008·Journal of the Royal Society, Interface·Hu Zhang, Kuo-Kang Liu
Dec 25, 2006·Optics Express·Stephen C ChapinEric R Dufresne
May 8, 2009·Nano Letters·Sourobh RaychaudhuriEdward T Yu
Jun 8, 2010·Nature Nanotechnology·Erik M FreerDavid P Stumbo
Jul 9, 2010·Journal of the American Chemical Society·Sang-Jae ParkSo-Jung Park
Oct 30, 2010·Journal of the American Chemical Society·Markus MüllnerAxel H E Müller
Feb 16, 2012·Chemical Society Reviews·Mahmoud Elsabahy, Karen L Wooley
Jul 11, 2012·Chemical Society Reviews·Yiyong Mai, Adi Eisenberg
Aug 8, 2012·Journal of the American Chemical Society·Joachim SchmelzHolger Schmalz
Oct 12, 2012·Journal of the American Chemical Society·Ritu ShresthaKaren L Wooley
Apr 23, 2013·Nature Nanotechnology·Jun YaoCharles M Lieber
Nov 5, 2013·Nature·André H GröschelAxel H E Müller
Nov 10, 2013·Nature Nanotechnology·Onofrio M MaragòAndrea C Ferrari
Mar 7, 2014·Nature Communications·Zachary M HudsonIan Manners
May 28, 2014·Nature Communications·Lin JiaMitchell A Winnik
Dec 3, 2015·Nature Communications·Oliver E C GouldIan Manners
Dec 15, 2015·Scientific Reports·J BergmanM Vershinin
Jun 28, 2016·Chemical Society Reviews·Rebekah L N HailesIan Manners
Dec 7, 2016·Angewandte Chemie·Judith SchöbelHolger Schmalz
Jun 27, 2017·Nature Communications·Xiaoyu LiIan Manners
Feb 6, 2018·ACS Nano·Jeffrey E Melzer, Euan McLeod

❮ Previous
Next ❯

Citations

Jul 28, 2020·Advanced Materials·Hongbao XinBaojun Li
Oct 29, 2020·Journal of Microscopy·M L Martin-Fernandez
Feb 12, 2021·Annual Review of Physical Chemistry·Hiroshi Masuhara, Ken-Ichi Yuyama

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.