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Mannose-binding lectin gene site mutations and the susceptibility of rheumatic heart disease

Zhonghua yi xue za zhi

Oct 5, 2005

Z JinJ Hu

PMID: 16200716

Abstract

To investigate the relationship between mannose-binding lectin (MBL) gene exon 1 site mutations and chronic rheumatic heart disease (CRHD). Polymerase chain reaction (PCR) and restrictive fragment length Polymorphism (RFLP) were used to investigate the MBL exon 1 alleles in 36 patients ...read more

Mentioned in this Paper

Pathogenic Aspects
Pathogenesis
Mannose Binding Lectin
Exons
Gene Mutation
Chronic Rheumatic Heart Disease
MBL2 protein, human
MBL2 gene
Mannose-Binding Protein Deficiency
Alleles
Paper Details
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Mannose-binding lectin gene site mutations and the susceptibility of rheumatic heart disease

Zhonghua yi xue za zhi

Oct 5, 2005

Z JinJ Hu

PMID: 16200716

DOI:

Abstract

To investigate the relationship between mannose-binding lectin (MBL) gene exon 1 site mutations and chronic rheumatic heart disease (CRHD). Polymerase chain reaction (PCR) and restrictive fragment length Polymorphism (RFLP) were used to investigate the MBL exon 1 alleles in 36 patients ...read more

Mentioned in this Paper

Pathogenic Aspects
Pathogenesis
Mannose Binding Lectin
Exons
Gene Mutation
Chronic Rheumatic Heart Disease
MBL2 protein, human
MBL2 gene
Mannose-Binding Protein Deficiency
Alleles

Similar Papers Found In These Feeds

Rheumatic Heart Disease

Rheumatic heart disease, the sequel of acute rheumatic fever, continues to be a common health problem in the developing world, causing morbidity and mortality among both children and adults. Discover the latest research on rheumatic heart disease here.

Complement Pathway: Mannose-Binding Lectin

The Mannose-Binding Lectin Complement Pathway is activated when mannose-binding lectin binds to mannose found on the surface of pathogens. Subsequent complement activation is similar to the classical complement pathway, but without the need for antigen-antibody complexes. Discover the latest research here.

Related Papers

American Journal of Obstetrics and Gynecology

Mannose-binding lectin haplotypes may be associated with cerebral palsy only after perinatal viral exposure

American Journal of Obstetrics and GynecologyMay 6, 2008
Catherine S GibsonSouth Australian Cerebral Palsy Research Group
Revista Da Sociedade Brasileira De Medicina Tropical

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Paper Details
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