Manometric findings in patients with isolated distal gastroesophageal reflux.

World Journal of Gastroenterology : WJG
Yasemin OzinBurhan Sahin

Abstract

To analyze manometric abnormalities in patients with isolated distal reflux and compare these findings in patients with erosive and non-erosive disease. Five hundred and fifty patients who presented to the outpatient clinic of Turkiye Yuksek Ihtisas Hospital with gastroesophageal reflux disease-like symptoms were enrolled. Each individual was evaluated with esophageal manometry, 24-h ambulatory pH monitoring, and upper gastrointestinal endoscopy. Manometric findings for the patients with isolated distal reflux were compared to findings in controls who were free of reflux disorders or hypersensitive esophagus. Findings for isolated distal reflux patients with and without erosive reflux disease were also compared. Of the 550 subjects enrolled, 97 (17.6%, mean age 48 years) had isolated distal reflux and 100 had no abnormalities on ambulatory pH monitoring (control group, mean age 45 years). There were no significant differences between the isolated distal reflux group and control group with respect to age, body mass index, and esophageal body contraction amplitude (EBCA). Mean lower esophageal sphincter pressure was significantly higher in the control group (12.7 +/- 10.3 mmHg vs 9.6 +/- 7.4 mmHg, P = 0.01). Fifty-five (56.7%) of...Continue Reading

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Citations

Dec 16, 2011·World Journal of Gastroenterology : WJG·Mustafa DumanEce Genç
Aug 2, 2012·World Journal of Gastroenterology : WJG·Paulo Fernando Martins PinheiroRegina Maria Pereira
May 2, 2015·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·F B van HoeijA J Bredenoord
Sep 8, 2016·Journal of Neurogastroenterology and Motility·Liuqin JiangLin Lin
Nov 9, 2010·Journal of Pediatric Gastroenterology and Nutrition·Maria Rita Di PaceEnrico De Grazia

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