Manual dexterity in late childhood is associated with maturation of the corticospinal tract.

NeuroImage
Ian FuelscherTimothy J Silk

Abstract

Despite the important role of manual dexterity in child development, the neurobiological mechanisms associated with manual dexterity in childhood remain unclear. We leveraged fixel-based analysis (FBA) to examine the longitudinal association between manual dexterity and the development of white matter structural properties in the corticospinal tract (CST). High angular diffusion weighted imaging (HARDI) data were acquired for 44 right-handed typically developing children (22 female) aged 9-13 across two timepoints (timepoint 1: mean age 10.5 years ± 0.5 years, timepoint 2: 11.8 ± 0.5 years). Manual dexterity was assessed using the Grooved Pegboard Test, a widely used measure of manual dexterity. FBA-derived measures of fiber density and morphology were generated for the CST at each timepoint. Connectivity-based fixel enhancement and mixed linear modelling were used to examine the longitudinal association between manual dexterity and white matter structural properties of the CST. Longitudinal mixed effects models showed that greater manual dexterity of the dominant hand was associated with increased fiber cross-section in the contralateral CST. Analyses further demonstrated that the rate of improvement in manual dexterity was as...Continue Reading

References

Dec 18, 2001·Human Brain Mapping·Thomas E Nichols, Andrew P Holmes
Nov 13, 2007·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Nanda N J RommelseJoseph A Sergeant
Mar 3, 2010·Annual Review of Clinical Psychology·Robert D GibbonsStephen DuToit
Apr 10, 2010·IEEE Transactions on Medical Imaging·Nicholas J TustisonJames C Gee
Jul 3, 2010·Pediatrics in Review·R Jason GerberChristine Erdie-Lalena
May 3, 2011·Behavioural Brain Research·Lisette J van der Knaap, Ineke J M van der Ham
Jul 29, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Catherine Lebel, Christian Beaulieu
Oct 8, 2011·NeuroImage·Mark JenkinsonStephen M Smith
Jan 18, 2012·NeuroImage·Bruce Fischl
Dec 15, 2012·NeuroImage·Robert E SmithAlan Connelly
Feb 18, 2014·NeuroImage·Anderson M WinklerThomas E Nichols
Mar 1, 2014·The Journal of Pediatrics·Lisa Marie LangevinDeborah Dewey
Oct 30, 2016·Neuropharmacology·David PurgerMichelle Monje
Oct 21, 2015·NeuroImage·Jesper L R Andersson, Stamatios N Sotiropoulos
Nov 26, 2015·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jelle VeraartDmitry S Novikov
Jan 7, 2016·Human Movement Science·David Gaul, Johann Issartel
Sep 19, 2016·NeuroImage·Valeria ParlatiniMichel Thiebaut de Schotten
Oct 6, 2016·Developmental Neurobiology·Quentin WelniarzEmmanuel Roze
Dec 22, 2017·Neuron·Cassandra Sampaio-Baptista, Heidi Johansen-Berg
Jan 7, 2018·NeuroImage·Catherine Lebel, Sean Deoni
Apr 25, 2018·Cerebral Cortex·Henrietta HowellsMarco Catani
Jun 28, 2018·Frontiers in Psychology·Satoshi NobusakoAkio Nakai
Aug 8, 2018·NeuroImage·Jakob WasserthalKlaus H Maier-Hein
Aug 17, 2018·NMR in Biomedicine·Flavio Dell'Acqua, J-Donald Tournier
Sep 23, 2019·Medical Image Analysis·Jakob WasserthalKlaus H Maier-Hein
Jan 24, 2020·NeuroImage·Dennis DimondSigne Bray
Mar 28, 2020·Human Brain Mapping·Sila GencDerek K Jones

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Citations

Mar 31, 2021·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Ian FuelscherTimothy J Silk
Jul 28, 2021·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Mervyn SinghChristian Hyde
Aug 7, 2021·Schizophrenia Bulletin·Petra Verena ViherSebastian Walther

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