Manual Versus Robotic Catheter Ablation for the Treatment of Atrial Fibrillation: The Man and Machine Trial

JACC. Clinical Electrophysiology
Andreas RilligRoland Richard Tilz

Abstract

Circumferential pulmonary vein isolation (CPVI) using irrigated radiofrequency is the most frequently used ablation technique for the treatment of atrial fibrillation worldwide. To date, no large randomized multicenter trials have evaluated the efficacy and safety of CPVI using robotic navigation (RN) systems compared with the current gold standard of manual ablation (MN). In this prospective, international multicenter noninferiority trial, 258 patients with paroxysmal or persistent atrial fibrillation were randomized for CPVI using either RN (RN group, n = 131) or manual ablation (MN group, n = 127). In all patients, CPVI was performed using irrigated radiofrequency ablation in combination with a 3-dimensional mapping system. The primary endpoint was the absence of atrial arrhythmia recurrence on or off antiarrhythmic drugs during a 12-month follow-up period. Secondary endpoints were the evaluation of periprocedural complications and procedural data such as procedure time, fluoroscopy time, and incidence of esophageal injury. Baseline characteristics were comparable between the RN group and MN group. Procedure time was significantly shorter in the MN group (129.3 ± 43.1 min vs. 140.9 ± 36.5 min; p = 0.026). 247 patients comple...Continue Reading

References

Nov 20, 2008·Journal of Cardiovascular Electrophysiology·Luigi Di BiaseJennifer E Cummings
Oct 2, 2009·Journal of Cardiovascular Electrophysiology·Daniel StevenStephan Willems
Mar 18, 2010·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Andreas RilligWerner Jung
Sep 30, 2010·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Andreas RilligWerner Jung
Mar 6, 2012·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Hugh CalkinsDavid Wilber
Jul 31, 2013·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Andreas RilligRoland Richard Tilz
Feb 18, 2014·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Taishi KuwaharaKazutaka Aonuma
Jun 25, 2014·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Waqas UllahRichard J Schilling
Oct 25, 2014·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Andreas RilligRoland Richard Tilz
May 14, 2016·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Waqas UllahUNKNOWN UK Multicentre Trials Group**

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Citations

Feb 6, 2020·Journal of Cardiovascular Electrophysiology·Guillaume BassilJim W Cheung
Aug 15, 2020·Pacing and Clinical Electrophysiology : PACE·Thomas FinkRoland Richard Tilz
Apr 7, 2019·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Thomas FinkAndreas Rillig
May 7, 2020·Herzschrittmachertherapie & Elektrophysiologie·Kathi GoldsteinDirk Vollmann
Feb 4, 2019·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Francesco SantoroAndreas Rillig
Jan 4, 2020·Cardiology and Therapy·Laura RottnerAndreas Rillig
May 14, 2020·Expert Review of Medical Devices·Laura RottnerAndreas Rillig
Mar 23, 2018·Pacing and Clinical Electrophysiology : PACE·Evgeny LyanNoureddin Sawan

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