Get paper from

journal cover

Mapping bias overestimates reference allele frequencies at the HLA genes in the 1000 Genomes Project phase I data

bioRxiv

Dec 23, 2014

Debora Yoshihara Caldeira BrandtDiogo Meyer

Get paper from

Abstract

Next Generation Sequencing (NGS) technologies have become the standard for data generation in studies of population genomics, as the 1000 Genomes Project (1000G). However, these techniques are known to be problematic when applied to highly polymorphic genomic regions, such as the Human ...read more

Mentioned in this Paper

Gene Polymorphism
TAPBP protein, human
HLA-DQB1 antigen
Dideoxy Chain Termination DNA Sequencing
Study
Single Nucleotide Polymorphism
RBM45 gene
Population Group
Genome
Human Leukocyte Antigen (HLA) A Antigen Typing (Procedure)
7
Paper Details
References
    • References
    • Citations

      References currently unavailable

      We're still populating references for this paper, please check back later.
    • References
    • Citations

      No citations available

      This paper may not have been cited yet.
  • Mapping bias overestimates reference allele frequencies at the HLA genes in the 1000 Genomes Project phase I data

    bioRxiv

    Dec 23, 2014

    Debora Yoshihara Caldeira BrandtDiogo Meyer

    PMID: 990013151

    DOI: 10.1101/013151

    Abstract

    Next Generation Sequencing (NGS) technologies have become the standard for data generation in studies of population genomics, as the 1000 Genomes Project (1000G). However, these techniques are known to be problematic when applied to highly polymorphic genomic regions, such as the Human ...read more

    Mentioned in this Paper

    Gene Polymorphism
    TAPBP protein, human
    HLA-DQB1 antigen
    Dideoxy Chain Termination DNA Sequencing
    Study
    7

    Related Papers

    Paper Details
    References
    • References
    • Citations

      References currently unavailable

      We're still populating references for this paper, please check back later.
    • References
    • Citations

      No citations available

      This paper may not have been cited yet.
  • Get paper from

    © 2019 Meta ULC. All rights reserved.
    /papers/mapping-bias-overestimates-reference-allele/990013151