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Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C

Nature Genetics

Jun 1, 2015

Borbala MifsudCameron S Osborne

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Abstract

Transcriptional control in large genomes often requires looping interactions between distal DNA elements, such as enhancers and target promoters. Current chromosome conformation capture techniques do not offer sufficiently high resolution to interrogate these regulatory interactions on ...read more

Mentioned in this Paper

Blood Cells
Cell Communication
Chromosomes
DNA
Early Promoters, Genetic
Genes
Genome
Genome, Human
Transcription, Genetic
Genome Mapping
71
5
3
845
1
Paper Details
References
    • References34
    • Citations106
    • References34
    • Citations106
  • Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C

    Nature Genetics

    Jun 1, 2015

    Borbala MifsudCameron S Osborne

    PMID: 25938943

    DOI: 10.1038/ng.3286

    Abstract

    Transcriptional control in large genomes often requires looping interactions between distal DNA elements, such as enhancers and target promoters. Current chromosome conformation capture techniques do not offer sufficiently high resolution to interrogate these regulatory interactions on ...read more

    Mentioned in this Paper

    Blood Cells
    Cell Communication
    Chromosomes
    DNA
    Early Promoters, Genetic
    71
    5
    3
    845
    1

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    Paper Details
    References
    • References34
    • Citations106
    • References34
    • Citations106
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