PMID: 6972093Jan 1, 1981Paper

Mapping of functional activity in brain with 18F-fluoro-deoxyglucose

Seminars in Nuclear Medicine
A AlaviA Wolf

Abstract

The efficacy of using the 18F-fluoro-deoxyglucose (18F-DG) for measuring regional cerebral glucose utilization in man during functional activation is demonstrated. Normal male volunteers subjected to sensory stimuli (visual, auditory, tactile) exhibited focal increases in glucose metabolism in response to the stimulus. Unilateral visual hemifield stimulation caused the contralateral striate cortex to become more active metabolically than the striate cortex ipsilateral to the stimulated hemifield. Similarly, stroking of the fingers and hand of one arm with a brush produced an increase in metabolism in the contralateral postcentral gyrus compared to the homologous ipsilateral region. The auditory stimulus, which consisted of monaural listening to either a meaningful or nonmeaningful story, caused an increase in glucose metabolism in the right temporal cortex independent of which ear was stimulated. These results demonstrate that the 18F-DG technique is capable of providing functional maps in vivo in the human brain.

References

Jan 1, 1975·Radiology·M M Ter-PogossianN A Mullani
Sep 1, 1973·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·S J Dimond, J G Beaumont
Jan 1, 1954·The Journal of Pediatrics·J M GARFUNKELJ ZIEGLER
Feb 1, 1957·A.M.A. Archives of Neurology and Psychiatry·N A LASSENE R TOTTEY
Sep 1, 1949·Anesthesiology·S S KETY

❮ Previous
Next ❯

Citations

May 23, 2007·The Journal of Laryngology and Otology·K M J GreenR T Ramsden
Oct 3, 2002·Annual Review of Psychology·Morton Ann Gernsbacher, Michael P Kaschak
Aug 30, 2008·Cochlear Implants International·K M J GreenD E L Hastings
Jan 1, 1982·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·M E PhelpsS C Huang
May 1, 1984·Stroke; a Journal of Cerebral Circulation·H YonasO M Reinmuth
Nov 1, 1982·Stroke; a Journal of Cerebral Circulation·D GurE E Cook
Jul 3, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Abass Alavi, Sandip Basu
Jan 30, 1999·Radiographics : a Review Publication of the Radiological Society of North America, Inc·P D ShreveR L Wahl
Sep 5, 2019·European Journal of Nuclear Medicine and Molecular Imaging·Abass AlaviPoul Flemming Høilund-Carlsen
Dec 1, 1982·Journal of Medical Systems·M M Ter-Pogossian
Jan 1, 1984·Neurosurgical Review·Y L YamamotoW H Feindel
Oct 1, 2015·Dementia & Neuropsychologia·Chetsadaporn PromteangtrongCarlos Buchpiguel
Jan 1, 1984·Comparative Biochemistry and Physiology. A, Comparative Physiology·B CanlonJ Schacht
Jan 1, 1986·Seminars in Nuclear Medicine·A AlaviM Reivich
Oct 1, 1994·Seminars in Nuclear Medicine·G B SahaR T Go

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.