Mapping of normal corneal K-structures by in vivo laser confocal microscopy

Cornea
Hideaki YokogawaKazuhisa Sugiyama

Abstract

To produce 2-dimensional reconstruction maps of normal human corneal fibrous structures beneath the Bowman layer (K-structures) by in vivo laser confocal microscopy and to show association of structures with the anterior corneal mosaic (ACM). Central corneal regions of 3 healthy volunteers were scanned. Acquired images of K-structures for each eye were arranged and mapped into a subconfluent montage. For each subject, electrical tracings of K-structures were superimposed on a slit-lamp photograph of the ACM produced by rubbing the eyelid. A mean of 677 +/- 211 images of K-structures were obtained for each eye. Mean dimensions of the mapped areas were 5.88 +/- 0.50 (horizontal) and 3.51 +/- 1.37 mm (vertical). In all subjects, K-structures formed a netlike pattern (mean area, 0.082 +/- 0.051 mm), and electrical tracings had good concordance with the ACM. This is the first study, to our knowledge, to elucidate the overall distribution of K-structures in normal human corneas. The netlike pattern of K-structures corresponded well with ACM pattern. These results support the hypothesis that the K-structures are the anterior collagen fiber bundles running at the posterior surface of the Bowman layer and thus are the structural basis f...Continue Reading

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Citations

Apr 19, 2013·Cornea·Katie EdwardsNathan Efron
Jul 9, 2010·International Ophthalmology Clinics·Michael W BelinDipika Patel
Aug 3, 2010·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Hideaki YokogawaKazuhisa Sugiyama
Jul 11, 2008·American Journal of Ophthalmology·Akira KobayashiKazuhisa Sugiyama
Apr 3, 2009·Clinical & Experimental Ophthalmology·Rudolf F GuthoffOliver Stachs
May 19, 2012·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Mitra TavakoliRayaz A Malik
Oct 16, 2013·Journal of Diabetes Science and Technology·Mitra TavakoliRayaz A Malik
Sep 28, 2018·Biomedical Optics Express·Sebastian BohnOliver Stachs
Mar 12, 2017·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·B KöhlerR Mikut
Nov 10, 2020·Medical Image Analysis·Lei MouJiang Liu
Jun 3, 2021·Diagnostics·Katharina A SterenczakAngrit Stachs

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