Mapping of retinal function in Best macular dystrophy using multifocal electroretinography

Vision Research
Hendrik P N SchollE Zrenner

Abstract

In order to evaluate the function of the retina in Best macular dystrophy (BMD) 18 patients were examined by means of the multifocal electroretinogram (mfERG). The mfERG peak amplitudes of the central and pericentral responses were significantly reduced in the BMD patients (p<0.001). The ERG amplitude decrease of the central response was significantly correlated with visual acuity loss and with the funduscopic staging. The implicit times in more eccentric groups were slightly but significantly increased. The markedly reduced mfERG amplitudes with only slightly increased implicit times may indicate cone photoreceptor cell loss or damage to the cone outer segments.

References

Jul 1, 1979·Archives of Ophthalmology·K G Noble, R E Carr
Mar 1, 1977·Archives of Ophthalmology·R C HsiehJ S Lyons
Jul 1, 1977·American Journal of Ophthalmology·M F Marmor, B Byers
Oct 1, 1976·American Journal of Ophthalmology·O B Hadden, J D Gass
Feb 1, 1976·Archives of Ophthalmology·G A FishmanM Fishman
Feb 22, 1990·The Journal of Comparative Neurology·C A CurcioA E Hendrickson
Sep 1, 1988·Archives of Ophthalmology·S O'GormanE L Berson
Apr 15, 1985·American Journal of Ophthalmology·J D GassB Davis
Jun 1, 1966·American Journal of Ophthalmology·A E KrillB A Klien
Dec 1, 1982·Ophthalmology·R C WatzkeR M Lang
Jul 1, 1982·Archives of Ophthalmology·T A WeingeistR C Watzke
Jul 1, 1982·Archives of Ophthalmology·G T FrangiehS L Fine
Nov 1, 1993·Ophthalmology·G A FishmanM Viana
Jun 1, 1996·Current Eye Research·B FalsiniL Buzzonetti
May 29, 1998·The British Journal of Ophthalmology·U KretschmannE Zrenner
Aug 5, 2000·Progress in Retinal and Eye Research·D C Hood

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Citations

Sep 1, 2007·Documenta Ophthalmologica. Advances in Ophthalmology·Timothy Y Y LaiDennis S C Lam
Apr 6, 2005·Ophthalmology·Agnes B RennerUlrich Kellner
Sep 18, 2010·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Thomas K M LeeIan M MacDonald
Apr 21, 2009·Progress in Retinal and Eye Research·Camiel J F BoonAnneke I den Hollander
Jan 11, 2007·Survey of Ophthalmology·Timothy Y Y LaiDennis S C Lam
Oct 2, 2015·Journal of Ophthalmic & Vision Research·Neda Mazahery TehraniMohammad Riazi-Esfahani
Feb 17, 2007·Korean Journal of Ophthalmology : KJO·Sang Jin KimHyeong Gon Yu
Jan 5, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Christiane Al-HaddadHasan Chahine
Feb 20, 2021·International Ophthalmology·Zübeyir YozgatSerpil Yazgan Akpolat

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