Mapping the clinical chronic obstructive pulmonary disease questionnaire onto generic preference-based EQ-5D values

Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research
Melinde R S BolandMaureen P M H Rutten-van Mölken

Abstract

To develop a model to predict EuroQol five-dimensional questionnaire (EQ-5D) values from clinical chronic obstructive pulmonary disease (COPD) questionnaire (CCQ) scores. We used data from three clinical trials (the Randomized Clinical Trial on Effectiveness of Integrated COPD Management in Primary Care [RECODE], the Assessment Of Going Home Under Early Assisted Discharge [GO-AHEAD], and the Health Status Guided COPD Care [MARCH]). Data were randomly split into an estimation sample and a validation sample. The conceptual similarity between patient-reported CCQ and preference-based EQ-5D scores was assessed using correlation and principal-component analysis. Different types of models were estimated with increasing complexity. We selected the final models on the basis of mean absolute error and root mean square error when comparing predicted and observed values from the same population (internal validity) and from different trial populations (external validity). We also developed models for different country-specific EQ-5D value sets. The principal-component analysis showed that the CCQ domains functional state and mental state are associated with four dimensions of the EQ-5D. The EQ-5D dimension pain/discomfort formed a separate...Continue Reading

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Citations

Oct 20, 2015·Current Medical Research and Opinion·J F M van BovenM J Postma
Jun 22, 2016·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Christopher K HoyleJean Brooks
Dec 24, 2018·The European Respiratory Journal·Job F M van BovenMohsen Sadatsafavi
Jun 7, 2019·Health and Quality of Life Outcomes·Jaeok LimGyeong-Seon Shin
Mar 24, 2018·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Admassu N LamuJan Abel Olsen
Oct 31, 2017·Current Opinion in Pulmonary Medicine·Janwillem W H KocksIoanna G Tsiligianni
Oct 29, 2019·Journal of Back and Musculoskeletal Rehabilitation·Betul TaspinarCihan C Aksoy
Dec 16, 2020·Journal of Clinical Medicine·Roy MeysSarah Houben-Wilke

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