Mapping the knowledge structure and trends of epilepsy genetics over the past decade: A co-word analysis based on medical subject headings terms

Medicine
Jing GanRong Luo

Abstract

Over the past 10 years, epilepsy genetics has made dramatic progress. This study aimed to analyze the knowledge structure and the advancement of epilepsy genetics over the past decade based on co-word analysis of medical subject headings (MeSH) terms. Scientific publications focusing on epilepsy genetics from the PubMed database (January 2009-December 2018) were retrieved. Bibliometric information was analyzed quantitatively using Bibliographic Item Co-Occurrence Matrix Builder (BICOMB) software. A knowledge social network analysis and publication trend based on the high-frequency MeSH terms was built using VOSviewer. According to the search strategy, a total of 5185 papers were included. Among all the extracted MeSH terms, 86 high-frequency MeSH terms were identified. Hot spots were clustered into 5 categories including: "ion channel diseases," "beyond ion channel diseases," "experimental research & epigenetics," "single nucleotide polymorphism & pharmacogenetics," and "genetic techniques". "Epilepsy," "mutation," and "seizures," were located at the center of the knowledge network. "Ion channel diseases" are typically in the most prominent position of epilepsy genetics research. "Beyond ion channel diseases" and "genetic techn...Continue Reading

References

Jun 14, 2006·Trends in Neurosciences·Samuel F BerkovicSteven Petrou
Feb 16, 2008·Lancet Neurology·Ingo HelbigSamuel F Berkovic
Oct 28, 2008·Progress in Neurobiology·Christopher A ReidSteven Petrou
Jun 30, 2010·Scientometrics·Nees Jan van Eck, Ludo Waltman
Feb 1, 2011·Current Opinion in Genetics & Development·Annapurna Poduri, Daniel Lowenstein
Sep 4, 2012·Handbook of Clinical Neurology·Antonietta Coppola, Solomon L Moshé
Feb 23, 2013·Current Opinion in Neurology·Ingo Helbig, Daniel H Lowenstein
Apr 27, 2013·BMC Medical Informatics and Decision Making·Chichen ZhangZhiguang Duan
Apr 16, 2014·Nature Reviews. Neurology·Rhys H Thomas, Samuel F Berkovic
Sep 10, 2014·Progress in Brain Research·Snezana Maljevic, Holger Lerche
Mar 6, 2015·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Sue RichardsUNKNOWN ACMG Laboratory Quality Assurance Committee
Jun 11, 2015·Seminars in Neurology·Ingo Helbig
Sep 1, 2015·Epilepsy Currents·Heather C Mefford
Apr 29, 2016·Scientometrics·Arzu Tugce GulerMagnus Palmblad
Sep 22, 2016·Advances in Neurobiology·Omkaram Gangisetty, Sengottuvelan Murugan
Oct 27, 2016·Molecular Syndromology·Ingo Helbig, Abou Ahmad N Tayoun
Dec 3, 2016·Nucleic Acids Research·Sebastian KöhlerPeter N Robinson
Jan 20, 2017·Lancet Neurology·UNKNOWN Epi4K consortium, UNKNOWN Epilepsy Phenome/Genome Project
Jan 24, 2017·Neuroscience Letters·K Kobow, I Blümcke
Apr 22, 2017·The Journal of General Physiology·Jeffrey Noebels
May 14, 2017·Neuroscience Letters·Alessandro OrsiniPasquale Striano
Jun 8, 2017·Neurochemical Research·William A Catterall
Aug 2, 2017·JAMA Pediatrics·Anne T BergSookyong Koh
Aug 2, 2017·Neuropsychiatric Disease and Treatment·Tian ChenYan Li
Oct 4, 2017·Expert Opinion on Therapeutic Targets·Hannah StambergerPeter De Jonghe
Dec 22, 2017·Pharmacological Reviews·Julia OyrerChristopher A Reid
Jan 2, 2018·Seizure : the Journal of the British Epilepsy Association·Elie AbdelnourMohamad A Mikati
Jan 23, 2018·Seizure : the Journal of the British Epilepsy Association·Lucia MargariMaria A Mariggiò
Feb 13, 2018·Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology·Jiaxin LiFang Yuan
Feb 27, 2018·Handbook of Clinical Neurology·Danielle Nolan, John Fink
Apr 28, 2018·Seizure : the Journal of the British Epilepsy Association·Yoonhyuk JangSang Kun Lee
May 10, 2018·Epilepsia·Saul A MullenUNKNOWN ILAE Genetics Commission
Jun 13, 2018·Seizure : the Journal of the British Epilepsy Association·Soheir S Abou El EllaOmar Ahmed M Soliman
Jul 12, 2018·Clinical Genetics·K A MyersD A Dyment
Sep 14, 2018·Frontiers in Molecular Neuroscience·Catalina SakaiEllen J Hoffman
Sep 15, 2018·International Journal of Molecular Sciences·Jie-Hua Xu, Feng-Ru Tang

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Citations

May 3, 2020·International Journal of Molecular Sciences·Ramon Cacabelos
Jul 28, 2020·JMIR MHealth and UHealth·Cheng PengZhongqing Wang
Jun 20, 2020·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Giulio FortunaGary D Klasser
Sep 28, 2020·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Muhammet Gultekin Kutluk, Aysegul Danis
Nov 6, 2020·The American Journal of Chinese Medicine·Xian ZhangJincheng Song
Nov 3, 2020·IScience·Changyu DengWei Lu
Apr 4, 2021·Journal of Personalized Medicine·Svetlana TarbeevaEkaterina Ilgisonis
Jul 25, 2021·International Journal of Environmental Research and Public Health·Ah-Ram Kim, Hae Yean Park

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Methods Mentioned

BETA
exome sequencing

Software Mentioned

VOSviewer
ArcGIS
Excel
Bibliographic Item Co - Occurrence Matrix Builder ( BICOMB )

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