Mapping the structural properties of the lumbosacral vertebral endplates

Spine
J Pamela GrantMarcel F Dvorak

Abstract

A biomechanical investigation using indentation tests in a human cadaveric model to seek variation in the structural properties across the lower lumbar and sacral endplates. To determine 1) if there are regional differences in endplate strength and 2) whether any differences identified are affected by spinal level (lumbar spine vs. sacrum) or endplate (superior vs. inferior). It has been postulated that some regions of the vertebral body may be stronger than others. Conclusive data, either supporting or disproving this theory, would be valuable for both spine surgeons and implant designers because one mode of failure of interbody implants is subsidence into one or both adjacent vertebrae. Indentation tests were performed at 27 standardized test sites in 62 bony endplates of intact human vertebrae (L3-S1) using a 3-mm-diameter, hemispherical indenter with a test rate of 0.2 mm/sec to a depth of 3 mm. The failure load and stiffness at each test site were determined using the load-displacement curves. Three-way analyses of variance were used to analyze the resulting data. Both the failure load and stiffness varied significantly across the endplate surfaces (P < 0.0001), with posterolateral regions being stronger and stiffer than t...Continue Reading

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Citations

Mar 12, 2008·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·H ChenY Bunai
Feb 9, 2010·Archives of Orthopaedic and Trauma Surgery·Jin-Yong DingYue Zhou
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