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Maresin1 Decreased Microglial Chemotaxis and Ameliorated Inflammation Induced by Amyloid-β42 in Neuron-Microglia Co-Culture Models

Journal of Alzheimer's Disease : JAD

Dec 5, 2019

Ping YinMingqin Zhu

Abstract

Inflammation resolution is regulated by specialized pro-resolving lipid mediators (SPMs) and the levels of SPMs are found decreased in Alzheimer's disease (AD) brain. We have previously found that one of the SPMs, Maresin1 (MaR1), improved neuronal survival and increase microglial phago...read more

Mentioned in this Paper

Study
Biochemical Pathway
Tumor Necrosis Factor-alpha
AKT1
Coculture Techniques
Anti-Inflammatory Agents
Neurons
Brain
Chemotaxis
Alzheimer's Disease
2
1
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Maresin1 Decreased Microglial Chemotaxis and Ameliorated Inflammation Induced by Amyloid-β42 in Neuron-Microglia Co-Culture Models

Journal of Alzheimer's Disease : JAD

Dec 5, 2019

Ping YinMingqin Zhu

PMID: 31796671

DOI: 10.3233/jad-190682

Abstract

Inflammation resolution is regulated by specialized pro-resolving lipid mediators (SPMs) and the levels of SPMs are found decreased in Alzheimer's disease (AD) brain. We have previously found that one of the SPMs, Maresin1 (MaR1), improved neuronal survival and increase microglial phago...read more

Mentioned in this Paper

Study
Biochemical Pathway
Tumor Necrosis Factor-alpha
AKT1
Coculture Techniques
Anti-Inflammatory Agents
Neurons
Brain
Chemotaxis
Alzheimer's Disease
2
1

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