Marginal donors for patients on regular waiting lists for liver transplantation

Transplant International : Official Journal of the European Society for Organ Transplantation
S AgnesM Castagneto

Abstract

The use of marginal donors is well accepted by most centers for emergency situations, but there is debate on their use for patients on regular waiting lists. We report our experience of the 1-year survival for patients on waiting lists (n = 147, 1-year survival = 32%), patients transplanted from good donors (n = 60, 1-year survival = 84%), and patients transplanted from marginal donors (n = 15, 1-year survival = 56%). We concluded that liver transplantation from marginal donors (a) is a safe procedure (b) has a 1-year survival that is significantly better than that on a waiting list (c) is ethically justified especially in countries with donor shortages, and (d) may allow transplantation of "special" high risk and poor long-term outcome patients.

References

Nov 26, 1994·Lancet·D F MirzaP McMaster
Jan 1, 1993·Transplant International : Official Journal of the European Society for Organ Transplantation·J PruimM J Slooff
Nov 24, 2011·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons

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Citations

Jan 23, 2008·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·J PratschkeP Neuhaus
Sep 15, 2012·Transplantation Proceedings·A W AvolioS Agnes
Aug 20, 2008·São Paulo Medical Journal = Revista Paulista De Medicina·Telesforo BacchellaMarcel Cerqueira César Machado
Aug 15, 2002·Transplantation Proceedings·Joseph F BuellJ M Millis
Sep 10, 1999·Transplantation·H V Melendez, N D Heaton
Jun 27, 2003·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Ronald W Busuttil, Koichi Tanaka

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