Marginal zone B-cell lymphoma of minor salivary gland representing tumor-forming amyloidosis of the oral cavity. A case report

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Masaru KojimaN Masawa

Abstract

We report here a case of mucosa-associated lymphoid tissue (MALT)-type lymphoma arising from the minor salivary gland of the oral cavity exhibiting tumor-forming amyloidosis. The patient was a 64-year-old Japanese woman who presented with 4-year history of a left soft palate mass. Despite multiple and multifocal recurrences including the lip, soft palate, tongue, oral base and vocal code and soft palate, the tumor remained localized in the upper aerodigestive tract, and the patient did not develop multiple myeloma during the course of disease. Histologically, the majority of the lesion was occupied by amyloid deposition. Only the periphery of the lesion contained numerous plasmacytoid cells, along with occasional centrocyte-like cells. In addition, lymphoepithelial lesion and follicular colonization were noted. The present case indicates that primary minor salivary gland MALT-type lymphoma appears to be the cause of tumor-forming amyloidosis of the upper aerodigestive tract including the larynx.

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Citations

Dec 26, 2007·Pathology Oncology Research : POR·Masaru KojimaHiroshi Inagaki
Oct 3, 2008·Oral and Maxillofacial Surgery·Kenji YamagataHiroshi Yoshida
Feb 25, 2014·The British Journal of Oral & Maxillofacial Surgery·Samuel S FolkardDaljit K Dhariwal
Feb 6, 2013·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Goro KawasakiMasahiro Umeda
Jan 30, 2019·Journal of Texture Studies·Jing GaoWeibiao Zhou
Nov 13, 2018·Case Reports in Hematology·Sebastiano CiccoVito Racanelli
Jan 15, 2021·Brazilian Journal of Otorhinolaryngology·Leandro Castro VelascoClaudiney Candido Costa

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