Marijuana and Lung Disease

Chest
Donald P Tashkin

Abstract

As marijuana smoking prevalence increases in the United States, concern regarding its potential risks to lung health has also risen, given the general similarity in the smoke contents between marijuana and tobacco. Most studies have found a significant association between marijuana smoking and chronic bronchitis symptoms after adjustment for tobacco. Although reports are mixed regarding associations between marijuana smoking and lung function, none have shown a relationship to decrements in FEV1 and few have found a relationship to a decreased ratio of FEV1/FVC, possibly related to an association between marijuana and an increased FVC. A few studies have found a modest reduction in specific airway conductance in relation to marijuana, probably reflecting endoscopic evidence of bronchial mucosal edema among habitual marijuana smokers. Diffusing capacity in marijuana smokers has been normal, and two studies of thoracic high-resolution CT scan have not shown any association of marijuana smoking with emphysema. Although bronchial biopsies from habitual marijuana smokers have shown precancerous histopathologic changes, a large cohort study and a pooled analysis of six well-designed case-control studies have not found evidence of a l...Continue Reading

Citations

Jan 17, 2019·The Journal of Rheumatology·Mary-Ann FitzcharlesUNKNOWN Canadian Rheumatology Association
Jul 13, 2019·The American Journal of Drug and Alcohol Abuse·Donald P Tashkin, Michael D Roth
Jul 30, 2019·The Journal of the American Osteopathic Association·Julianne Moy
Sep 21, 2019·The European Respiratory Journal·Wan C TanUNKNOWN Members of the CanCOLD Collaborative Research Group not listed as authors:
Oct 17, 2019·Annals of the American Thoracic Society·Theodore J Witek, Robert Schwartz
Apr 15, 2020·Addiction·Kathryn Gracie, Robert J Hancox
Jun 5, 2019·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·Tim RascheMartin Mücke
Sep 5, 2019·Scientific Reports·Taylor M NewmanGuy R Adami
Oct 28, 2019·Journal of Primary Care & Community Health·Deepika SlawekRobert Cook
Dec 25, 2019·Cannabis and Cannabinoid Research·Karim S LadhaHance Clarke
Jan 22, 2021·Addiction Science & Clinical Practice·Ellen Mello BorgonhiFelix Henrique Paim Kessler
Mar 23, 2021·Plastic and Reconstructive Surgery. Global Open·Libby R Copeland-HalperinJoseph H Shin
Apr 19, 2021·Revue des maladies respiratoires·M UndernerN Jaafari
Jan 30, 2021·The European Respiratory Journal·Léa BetserPauline Pradere
Jul 3, 2021·Journal of Community Hospital Internal Medicine Perspectives·Chahat PuriDonald Slack
Jul 23, 2021·ERJ Open Research·Matthew F FantauzziJeremy A Hirota
Mar 11, 2019·Journal of Clinical Anesthesia·Marco Echeverria-VillalobosSergio D Bergese

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