Marijuana Use in Adults Living with Sickle Cell Disease

Cannabis and Cannabinoid Research
John D RobertsAriadna Forray

Abstract

Introduction: Legal access to marijuana, most frequently as "medical marijuana," is becoming more common in the United States, but most states do not specify sickle cell disease as a qualifying condition. We were aware that some of our patients living with sickle cell disease used illicit marijuana, and we sought more information about this. Materials and Methods: We practice at an urban, academic medical center and provide primary, secondary, and tertiary care for ∼130 adults living with sickle cell disease. We surveyed our patients with a brief, anonymous, paper-and-pen instrument. We reviewed institutional records for clinically driven urine drug testing. We tracked patient requests for certification for medical marijuana. Results: Among 58 patients surveyed, 42% reported marijuana use within the past 2 years. Among users, most endorsed five medicinal indications; a minority reported recreational use. Among 57 patients who had at least one urine drug test, 18% tested positive for cannabinoids only, 12% tested positive for cocaine and/or phencyclidine only, and 5% tested positive for both cannabinoids and cocaine/phencyclidine. Subsequent to these studies, sickle cell disease became a qualifying condition for medical marijuan...Continue Reading

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Citations

Aug 1, 2019·Expert Review of Hematology·Carlton Dampier
Sep 15, 2020·Cannabis and Cannabinoid Research·Susanna A CurtisJohn D Roberts
Dec 5, 2020·Journal of Clinical Medicine·Donovan A ArguetaKalpna Gupta
Aug 27, 2021·Nature·Bianca Nogrady
Apr 10, 2019·Neuroscience Letters·Lydia H Pecker, Deepika S Darbari

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Methods Mentioned

BETA
transgenic

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