Marine Isonitriles and Their Related Compounds

Marine Drugs
Jens EmsermannTill Opatz

Abstract

Marine isonitriles represent the largest group of natural products carrying the remarkable isocyanide moiety. Together with marine isothiocyanates and formamides, which originate from the same biosynthetic pathways, they offer diverse biological activities and in spite of their exotic nature they may constitute potential lead structures for pharmaceutical development. Among other biological activities, several marine isonitriles show antimalarial, antitubercular, antifouling and antiplasmodial effects. In contrast to terrestrial isonitriles, which are mostly derived from α-amino acids, the vast majority of marine representatives are of terpenoid origin. An overview of all known marine isonitriles and their congeners will be given and their biological and chemical aspects will be discussed.

References

Oct 26, 1977·Journal of the American Chemical Society·S J Wratten, D J Faulkner
Dec 1, 1992·Journal of Natural Products·C K AngerhoferO Sticher
Jan 1, 1991·Journal of Natural Products·K A AlviP Crews
Jun 1, 1988·Natural Product Reports·M S Edenborough, R B Herbert
Jan 1, 1995·Journal of Natural Products·R S Compagnone, D J Faulkner
Apr 1, 1994·Journal of Natural Products·G Trimurtulu, D J Faulkner
Jul 1, 1996·Journal of Natural Products·A D WrightR Desqueyroux-Faúndez
May 1, 1997·Journal of Natural Products·A D PatilD S Eggleston
Dec 30, 1998·Journal of Natural Products·D Wolf, F J Schmitz
Oct 9, 1999·Journal of Natural Products·J Tanaka, T Higa
Jun 29, 2002·Journal of Natural Products·Natalia V PetrichtchevaYoshinori Fujimoto
Aug 24, 2002·Journal of Natural Products·L CiasulloL Gomez-Paloma
Sep 19, 2002·Chemical & Pharmaceutical Bulletin·Makoto IwashimaTakao Yamori
Jan 17, 2003·Organic Letters·Kota KodamaRob W M Van Soest
Mar 25, 2004·Natural Product Reports·Mary J Garson, Jamie S Simpson
May 29, 2004·Journal of Natural Products·Hidemichi MitomeRob W M Van Soest
Oct 23, 2004·Journal of Natural Products·Emiliano ManzoGuido Cimino
Aug 26, 2006·Journal of Asian Natural Products Research·X-H YanG Cimino
Dec 1, 2007·Journal of Natural Products·Shingo KozawaJun'ichi Kobayashi
Jan 29, 2008·Journal of Natural Products·Hung The DangJee H Jung
Feb 22, 2008·Journal of Natural Products·Eva ZubíaJ Luis Carballo
Jun 17, 2008·Journal of Natural Products·Haruaki IshiyamaJun'ichi Kobayashi
Nov 15, 2008·Journal of Natural Products·Eva ZubíaJ Luis Carballo
Feb 10, 2009·Journal of Natural Products·Anthony D Wright, Naomi Lang-Unnasch
Sep 2, 2009·Chemical & Pharmaceutical Bulletin·Chinni Mahesh KondempudiVenkateswarlu Yenamandra
Jan 22, 2010·Archives of Pharmacal Research·Ji-Zheng SunYue-Wei Guo
Dec 14, 2011·Bioorganic & Medicinal Chemistry·Alejandro M S MayerAbimael D Rodríguez
Jan 13, 2012·Journal of Natural Products·Anthony D WrightCherie A Motti
Mar 2, 2012·Journal of Natural Products·Naphatson ChanthathamrongsiriAnuchit Plubrukarn
Oct 20, 2012·Chemistry & Biodiversity·Jin-Rong ZhangGuo-Qiang Li
Nov 21, 2012·Journal of Natural Products·Keisuke NishikawaFuyuhiko Matsuda
Nov 10, 2013·Journal of Natural Products·Sunan JaisamutAnuchit Plubrukarn
Jan 21, 2014·Chemical & Pharmaceutical Bulletin·Wangta LiuJui-Hsin Su

❮ Previous
Next ❯

Citations

Jun 1, 2016·Journal of the American Chemical Society·Hai-Hua LuRyan A Shenvi
Mar 3, 2017·Journal of the American Chemical Society·Christopher A Reiher, Ryan A Shenvi
Aug 9, 2020·Organic & Biomolecular Chemistry·Bilal AltundasFraser F Fleming
Jan 19, 2021·Journal of Asian Natural Products Research·Viqqi KurniandaJunichi Tanaka
Nov 11, 2017·The Journal of Organic Chemistry·Andrew M WhiteChristopher D Vanderwal
May 18, 2018·The Journal of Organic Chemistry·Christian R Zwick, Hans Renata
Nov 10, 2020·Organic Letters·Yi-Xin SiSong-Lin Zhang
Sep 21, 2019·Journal of the American Chemical Society·Joonseok OhJason M Crawford
Nov 28, 2021·World Journal of Microbiology & Biotechnology·Parminder Kaur NarangVishakha Raina

❮ Previous
Next ❯

Methods Mentioned

BETA
X-ray
NMR

Related Concepts

Related Feeds

Candidiasis

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Antitubercular Agents (ASM)

Antitubercular agents are pharmacologic agents for treatment of tuberculosis. Discover the latest research on antitubercular agents here.

Antimalarial Agents (ASM)

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Candidiasis (ASM)

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Antimalarial Agents

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Candida albicans

Candida albicans is an opportunistic, fungal pathogen of humans that frequently causes superficial infections of oral and vaginal mucosal surfaces of debilitated and susceptible individuals. Discover the latest research on Candida albicans here.

Antitubercular Agents

Antitubercular agents are pharmacologic agents for treatment of tuberculosis. Discover the latest research on antitubercular agents here.

Related Papers

Natural Product Reports
Nobuhiro Fusetani
BMJ : British Medical Journal
A F Shaughnessy, D C Slawson
Journal of General Internal Medicine
L Scarpinato
© 2022 Meta ULC. All rights reserved