Marine metagenomics: strategies for the discovery of novel enzymes with biotechnological applications from marine environments.

Microbial Cell Factories
Jonathan KennedyAlan Dw Dobson

Abstract

Metagenomic based strategies have previously been successfully employed as powerful tools to isolate and identify enzymes with novel biocatalytic activities from the unculturable component of microbial communities from various terrestrial environmental niches. Both sequence based and function based screening approaches have been employed to identify genes encoding novel biocatalytic activities and metabolic pathways from metagenomic libraries. While much of the focus to date has centred on terrestrial based microbial ecosystems, it is clear that the marine environment has enormous microbial biodiversity that remains largely unstudied. Marine microbes are both extremely abundant and diverse; the environments they occupy likewise consist of very diverse niches. As culture-dependent methods have thus far resulted in the isolation of only a tiny percentage of the marine microbiota the application of metagenomic strategies holds great potential to study and exploit the enormous microbial biodiversity which is present within these marine environments.

References

Jun 17, 1998·Proceedings of the National Academy of Sciences of the United States of America·W B WhitmanW J Wiebe
Aug 24, 2000·Organic Letters·G Y WangJ Davies
Dec 6, 2001·Nature·F Azam, R A Long
Jun 29, 2002·The Journal of Biological Chemistry·Tony CollinsCharles Gerday
Aug 22, 2002·Journal of the American Chemical Society·Sean F BradyJon Clardy
Aug 30, 2002·Applied and Environmental Microbiology·Doreen E GillespieJo Handelsman
Sep 27, 2002·Current Opinion in Biotechnology·Karl-Erich Jaeger, Thorsten Eggert
Feb 13, 2003·Extremophiles : Life Under Extreme Conditions·Anwar Sunna, Peter L Bergquist
May 10, 2003·Chemosphere·Karl Heinz van Pée, Susanne Unversucht
Nov 5, 2003·Nature Biotechnology·Manuel FerrerKenneth N Timmis
Apr 7, 2004·Science·J Craig VenterHamilton O Smith
Aug 6, 2004·Applied and Environmental Microbiology·Manuel FerrerPeter N Golyshin
Aug 13, 2004·Environmental Microbiology·Esther M GaborDick B Janssen
Dec 8, 2004·Extremophiles : Life Under Extreme Conditions·Cédric F V HobelJakob K Kristjánsson
Dec 14, 2004·Microbiology and Molecular Biology Reviews : MMBR·Jo Handelsman
Mar 19, 2005·Marine Biotechnology·Detmer SipkemaRené H Wijffels
May 11, 2005·Proceedings of the National Academy of Sciences of the United States of America·Eric W SchmidtJacques Ravel
May 28, 2005·Canadian Journal of Microbiology·Hidenori HayashiYoshimi Benno
Jun 1, 2005·Trends in Biotechnology·Don CowanPia Wittwer
Jun 3, 2005·Nature Reviews. Microbiology·Patrick Lorenz, Jürgen Eck
Jul 1, 2005·Chembiochem : a European Journal of Chemical Biology·Paul F LongMarcel Jaspars
Sep 16, 2005·Nature·Edward F DeLong, David M Karl
Jan 13, 2006·Omics : a Journal of Integrative Biology·Jillian F BanfieldMichael P Thelen
Jan 19, 2006·Extremophiles : Life Under Extreme Conditions·Shinsuke MakiYasuhiro Takada
Mar 18, 2006·Applied Microbiology and Biotechnology·Karl-Heinz van Pée, Eugenio P Patallo
Apr 7, 2006·Journal of Industrial Microbiology & Biotechnology·David J Newman, Russell T Hill
Apr 13, 2006·Extremophiles : Life Under Extreme Conditions·Marit Sjo LorentzenNils Peder Willassen
May 19, 2006·Extremophiles : Life Under Extreme Conditions·Maryam Goudarzi, Timothy L Born

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Citations

Aug 24, 2012·World Journal of Microbiology & Biotechnology·Xiaoluo HuangZiduo Liu
Aug 20, 2010·Environmental Technology·William D Grant, Shaun Heaphy
May 31, 2012·Nucleic Acids Research·Yanbin YinYing Xu
Jul 11, 2009·Science·Jesse W-H Li, John C Vederas
Jul 19, 2011·Microbial Cell Factories·Arnaldo GlogauerNadia Krieger
Aug 11, 2011·PloS One·Alba ArduraEva Garcia-Vazquez
Sep 13, 2011·PLoS Pathogens·Tung G PhanEric L Delwart
Jun 28, 2014·Biomolecules·Jose L Adrio, Arnold L Demain
Feb 19, 2011·Annual Review of Marine Science·Jack A Gilbert, Christopher L Dupont
Dec 17, 2014·Microbial Cell Factories·Viviane Paula MartiniNadia Krieger
Mar 2, 2010·Current Opinion in Biotechnology·Hyun Sook LeeJung-Hyun Lee
Nov 1, 2015·Gene·Katsuhiko Mineta, Takashi Gojobori
Mar 17, 2009·Biotechnology Journal·Jagtar SinghNavneet Batra
Mar 1, 2009·Microbial Biotechnology·Roland J Siezen, Greer Wilson
Jun 10, 2011·Journal of Basic Microbiology·Héctor Antonio CristóbalCarlos Mauricio Abate
Dec 5, 2014·Extremophiles : Life Under Extreme Conditions·Jonathan MaiangwaThean Chor Leow
Apr 30, 2015·World Journal of Microbiology & Biotechnology·Jing SuQun Jiang
Apr 10, 2012·Biotechnology Advances·Ana C FreitasArmando C Duarte
Sep 20, 2016·Gene·Soha Al-AmoudiVladimir B Bajic
Jan 26, 2010·Marine Drugs·Marieke KoopmansRene H Wijffels
Jun 27, 2017·Marine Genomics·Marco Fondi, Renato Fani
Jul 7, 2011·Marine Drugs·Antonio Trincone
Aug 15, 2013·Marine Drugs·Muhammad Abdul Mojid MondolMohammad Tofazzal Islam
Aug 15, 2017·Journal of Basic Microbiology·Tharcilla B A PessoaJoão C T Dias

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