Abstract
Cutaneous malignancies are considered rare among Africans. Trauma, its sequelae, and other chronic non-healing wounds are known to predispose to malignant degeneration. Not much is known of the demographics of Marjolin's ulcers in sub-Saharan Africa. Pathology records on patients suspected to have Marjolin's ulcers submitted to the Pathology Department were extracted from a database of 75,124 specimens. A review of the English literature on Marjolin's ulcers from Nigeria, a sub-Saharan country, was also performed. Of 210 specimens from suspected Marjolin's ulcers, 167 records had a histological diagnosis of malignancy, with a male to female ratio of 1:1.4, and a mean age of 48 years (range: 4-97 years). There were 163 (97.6%) squamous cell carcinomas, 3 (1.8%) sarcomas, and 1 (0.6%) malignant melanoma. Burn scars, chronic ulcers, osteomyelitis, and "other" ulcers constituted 82 (49%), 70 (42%), 9 (5.4%), and 6 (3.6%), respectively. Subjects in six sub-Saharan Marjolin's ulcer studies had a mean age between 36 and 42 years, with a mean latent period 16 years. Marjolin's ulcers in sub-Saharan African have a shorter latent period, and they occur in younger patients. Provision of early stable wound cover is essential for prevention...Continue Reading
References
Mar 1, 1975·Cancer·I D FlemingJ S Rankin
Jun 11, 1992·Journal of the American Academy of Dermatology·D E RoweC L Day
May 1, 1991·The Journal of Burn Care & Rehabilitation·J R Fishman, M G Parker
Jan 1, 1989·Archives of Surgery·M J EdwardsF C Ames
Sep 1, 1987·British Journal of Plastic Surgery·L M Iregbulem
May 1, 1981·Annals of Surgery·R F RyanE T Krementz
Oct 20, 2000·Plastic and Reconstructive Surgery·R L Love, A F Breidahl
Jan 5, 2002·The Journal of Burn Care & Rehabilitation·C OzekA Cagdas
Apr 11, 1959·Lancet·A W GARDNER
Aug 1, 1965·Annals of Surgery·T GIBLIND ARMSTRONG
Jan 5, 2005·British Journal of Plastic Surgery·Esra CelikAdnan Uzunismail
May 18, 2005·Burns : Journal of the International Society for Burn Injuries·Areta Kowal-Vern, Bryan K Criswell
May 18, 2005·Burns : Journal of the International Society for Burn Injuries·Eser AydoğduTayfun Aköz
Apr 25, 2006·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·I I OnahW I B Onuigbo
May 25, 2006·Burns : Journal of the International Society for Burn Injuries·Wilson I B Onuigbo
May 26, 2006·International Wound Journal·Stuart EnochKeith G Harding
Dec 6, 2007·International Journal of Dermatology·Maurice AsuquoPaul Jibril
Dec 7, 2007·Journal of Medical Case Reports·Peter M Nthumba
May 22, 2009·Clinical and Experimental Dermatology·M E AsuquoE E Bassey
Jun 9, 2009·Burns : Journal of the International Society for Burn Injuries·Ifeanyi I OnahWilson I B Onuigbo
Jul 2, 2009·Plastic and Reconstructive Surgery·Eray Copcu
Sep 5, 2009·Plastic and Reconstructive Surgery·Ramesh Kumar Sharma
Oct 13, 2009·World Journal of Surgery·Peter M Nthumba
Nov 3, 2009·Indian Journal of Plastic Surgery : Official Publication of the Association of Plastic Surgeons of India·M Daya, T Balakrishan
Citations
Jun 4, 2011·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Sarah C WallingfordAdèle C Green
Dec 7, 2010·World Journal of Surgical Oncology·Peter M Nthumba
Aug 23, 2011·Journal of Medical Case Reports·Peter M Nthumba
Dec 30, 2014·Journal of Cutaneous and Aesthetic Surgery·Vasu Reddy ChallaMadhusudana Bommasandra Ashwatha Reddy
Feb 18, 2012·World Journal of Surgical Oncology·Phillipo L ChalyaJaphet M Gilyoma
Oct 9, 2012·Burns : Journal of the International Society for Burn Injuries·Elizabeth L DalePeter M Nthumba
Feb 27, 2015·Burns : Journal of the International Society for Burn Injuries·Kishore Kumar DasSazzad Khandkar
May 20, 2015·Burns : Journal of the International Society for Burn Injuries·Peter M Nthumba
Jun 19, 2013·Burns : Journal of the International Society for Burn Injuries·Saadallah M Al-Zacko
May 14, 2016·Journal of Wound Care·J ZhuY Liu
Oct 18, 2014·World Journal of Clinical Cases·Muhammad Saaiq, Bushra Ashraf
Oct 1, 2019·Annals of Plastic Surgery·Gaurav ChaturvediShashank Lamba
Oct 22, 2013·Journal of Cutaneous Medicine and Surgery·Aysin Karasoy YesiladaHazim Orhan Kizilkaya
Nov 1, 2020·Journal of Burn Care & Research : Official Publication of the American Burn Association·Chairat BurusapatKantang Satayasoontorn
Nov 20, 2020·Advances in Skin & Wound Care·Kamran KhanJeyhan Wood
Sep 19, 2021·International Wound Journal·Ahmed K MousaSherif E Sayed