Marked increases in heart rate associated with sevoflurane but not with halothane following suxamethonium administration in children

European Journal of Anaesthesiology
A RiegerK Eyrich

Abstract

The changes in heart rate and arterial blood pressure following the administration of suxamethonium in healthy children (mean age 3.8 +/- 0.3 years) during inhalational induction with either sevoflurane (n = 22) or halothane (n = 19) were studied. Heart rate 60s following suxamethonium administration increased significantly in the sevoflurane but not in the halothane group. In the halothane group, four children required intravenous (i.v.) atropine as as result of bradycardia. None of the children in the sevoflurane group developed bradycardia following suxamethonium (P < 0.05). Values of oxygenation, ventilation and age corrected minimal alveolar concentration were comparable at all measurement times. The haemodynamic response to the administration of suxamethonium in children anaesthetized with sevoflurane seems to reflect the stimulation of the autonomic ganglia by suxamethonium whereas this positive chronotropic effect is attenuated or reversed by halothane.

References

Nov 1, 1992·Anesthesiology·H Rosenberg, G A Gronert
Feb 1, 1992·British Journal of Anaesthesia·T Katoh, K Ikeda
Jan 1, 1992·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·K B ShankarA Y Kumar
Jan 1, 1992·Anesthesia and Analgesia·P F ConzenK Messmer
Nov 1, 1987·Anesthesia and Analgesia·E DelphinP Rothstein
May 1, 1969·Anesthesiology·G A GregoryE S Munson
Oct 1, 1969·Anesthesiology·H F NicodemusT C Smith
Apr 1, 1983·Anesthesia and Analgesia·R H Friesen, J L Lichtor
May 1, 1994·Anesthesiology·R L KeenanP M Simpson
Apr 1, 1994·Anesthesiology·E I Eger
Jul 1, 1994·Anesthesiology·C P HarkinD C Warltier
Mar 1, 1993·Anesthesiology·J P MorrayF W Cheney
Feb 1, 1993·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·M Doi, K Ikeda

❮ Previous
Next ❯

Citations

Mar 11, 2006·Der Anaesthesist·B RudlofM Jacquet

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bradyarrhythmias

Bradyarrhythmias are slow heart rates. Symptoms may include syncope, dizziness, fatigure, shortness of breath, and chest pains. Find the latest research on bradyarrhythmias here.