Markedly High B-type Natriuretic Peptide Level in a Patient with Duchenne Muscular Dystrophy and Left Ventricular Non-Compaction

Internal Medicine
Ikuo MisumiHisao Ogawa

Abstract

A boy with Duchenne muscular dystrophy was admitted to our hospital due to a transient loss of consciousness. Transthoracic echocardiography revealed left ventricular (LV) dilatation and diffuse hypokinesis of the LV wall. The LV wall was thin, and both non-compaction of the LV wall and marked thinning of the posterior LV wall resulting from a lesion were observed. The plasma B-type natriuretic peptide (BNP) level ultimately increased to 7,795 pg/mL, and the patient died of cardiac arrest following ventricular tachycardia. Severe heart failure, a critical condition, and thinning of the LV wall may have contributed to the markedly high plasma BNP level in this case.

References

Mar 7, 2002·Lancet·Alan E H Emery
Nov 3, 2006·International Journal of Cardiology·Tayyab MohyuddinRobert C Bahler

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Citations

Sep 24, 2020·ESC Heart Failure·Katharina RapatzClaudia Stöllberger
May 7, 2016·Internal Medicine·Josef Finsterer, Sinda Zarrouk-Mahjoub

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