Markers for presymptomatic prediction of preeclampsia and intrauterine growth restriction

Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy
May Lee TjoaInge J van Wijk

Abstract

Preeclampsia and intrauterine growth restriction are both characterized by placental malfunction. The pathological processes of abnormal trophoblast invasion, partial absence of maternal spiral artery modification, increased apoptosis of trophoblast cells, and placental ischemia are all associated with the release of specific molecules. These proteins, as well as cell-free fetal DNA and RNA might be detected in the maternal peripheral circulation, quantified, and used for early identification and prediction of preeclampsia and intrauterine growth restriction, prior to the appearance of the clinical symptoms. As preeclampsia and intrauterine growth restriction are associated with increased maternal, perinatal, and neonatal morbidity and mortality, early identification of these pregnancy associated complications will permit the design of appropriate preventive measures. In this review a variety of factors reported to be useful as potential markers for early detection of pregnancies at increased risk will be discussed. Molecules associated with the establishment of the placenta and essential in fetal-maternal interactions, like interleukin 2-receptor, insulinlike growth factor-1, and insulinlike growth factor binding protein-1, pl...Continue Reading

References

Feb 1, 1990·American Journal of Obstetrics and Gynecology·C J Lockwood, J H Peters
Apr 1, 1985·British Journal of Obstetrics and Gynaecology·B N WaltersM De Swiet
Jun 5, 1993·Lancet·J M Roberts, C W Redman
Jul 25, 1996·The New England Journal of Medicine·B M Sibai
Jul 1, 1996·American Journal of Obstetrics and Gynecology·C J de GrootR N Taylor
Jul 1, 1996·American Journal of Obstetrics and Gynecology·F MullerP Giraudet
Jun 1, 1996·The Journal of Obstetrics and Gynaecology Research·T Yasumizu, J Kato
Jan 1, 1997·European Journal of Obstetrics, Gynecology, and Reproductive Biology·R AustgulenC W Redman
Apr 1, 1997·British Journal of Obstetrics and Gynaecology·S DjurovicK Berg
Aug 16, 1997·Lancet·Y M LoJ S Wainscoat
Aug 5, 1998·American Journal of Reproductive Immunology : AJRI·R F FraserP Coney
Aug 29, 1998·Obstetrics and Gynecology·I L WihmanM Faxén
Oct 9, 1998·American Journal of Reproductive Immunology : AJRI·K P ConradD F Benyo
Nov 4, 1998·British Journal of Obstetrics and Gynaecology·H CuckleR Jones
Dec 17, 1998·American Journal of Obstetrics and Gynecology·D S TorryR J Torry
Feb 9, 1999·Gynecologic and Obstetric Investigation·T GredmarkL Hellström
Mar 17, 1999·American Journal of Obstetrics and Gynecology·J F McCarthyJ M Roberts
Oct 16, 1999·British Journal of Obstetrics and Gynaecology·A ReuvekampA J Duits
Oct 16, 1999·American Journal of Obstetrics and Gynecology·R S EgermanB M Sibai
Dec 11, 1999·JAMA : the Journal of the American Medical Association·M VisserT B Harris
Feb 16, 2000·Obstetrics and Gynecology·R HietalaT Laatikainen
Apr 14, 2000·American Journal of Obstetrics and Gynecology·S KhatunT Terao
Apr 29, 2000·Journal of Perinatology : Official Journal of the California Perinatal Association·I PhocasE Salamalekis
Jun 10, 2000·BJOG : an International Journal of Obstetrics and Gynaecology·N J SebireK H Nicolaides
Jun 24, 2000·Journal of the Society for Gynecologic Investigation·G M Lambert-MesserlianJ A Canick
Jun 30, 2000·Human Reproduction·S MuttukrishnaC W Redman
Jul 26, 2000·Obstetrics and Gynecology·A D AllaireB A Lessey
Aug 23, 2000·Metabolism: Clinical and Experimental·R J TeppaJ M Roberts
Aug 29, 2000·Obstetrics and Gynecology·W A Grobman, E Y Wang

❮ Previous
Next ❯

Citations

Apr 12, 2008·BMJ : British Medical Journal·Lucy C Chappell, Andrew H Shennan
Feb 10, 2007·Reproductive Biology and Endocrinology : RB&E·Laura LunghiFortunato Vesce
Nov 24, 2011·Clinical Chemistry and Laboratory Medicine : CCLM·Yves GiguèreJean-Claude Forest
Sep 1, 2005·European Journal of Endocrinology·Udo MeissnerJörg Dötsch
Mar 8, 2011·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Mohamed Nabih El-Gharib, Ma Morad
Apr 18, 2007·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Veronica LisiMaurizio Clementi
Aug 13, 2008·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·Patrick EmontsJean-Michel Foidart
Jan 1, 2008·Expert Opinion on Medical Diagnostics·Cees Bm Oudejans
Oct 8, 2015·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Sebastian KwiatkowskiBarbara Dolegowska
Sep 4, 2007·Seminars in Fetal & Neonatal Medicine·Andrew C G Breeze, Christoph C Lees
Dec 21, 2005·American Journal of Reproductive Immunology : AJRI·Yuehong MaSeth Guller
Feb 13, 2013·BJOG : an International Journal of Obstetrics and Gynaecology·A Conde-AgudeloJ Villar
Dec 8, 2010·Proteomics. Clinical Applications·Linda Dexlin-MellbyChrister Wingren
Feb 24, 2016·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Brad D PearceUsha Ramakrishnan
Oct 1, 2006·Expert Review of Pharmacoeconomics & Outcomes Research·Scott M Nelson, Ian A Greer
Dec 7, 2013·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·Gabriela Ruiz-QuiñonezMargarita Levario-Carrillo
Jul 4, 2006·American Journal of Obstetrics and Gynecology·Roberta B Ness, Baha M Sibai
Sep 16, 2016·Nigerian Medical Journal : Journal of the Nigeria Medical Association·S O AjibolaA S Akanmu
May 20, 2008·Journal de gynécologie, obstétrique et biologie de la reproduction·P EmontsJ-M Foidart
Mar 25, 2005·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·S IllanesP W Soothill
Jun 15, 2005·Journal of Korean Medical Science·Yoon-Mi Hur
Jul 31, 2020·Neurology·Aleksandra MineykoAdam Kirton
Jan 17, 2014·Journal of Obstetrics and Gynaecology of India·Sravanthi KasamMadisetty Venkat Sudeep
Nov 19, 2019·Social and Personality Psychology Compass·Michele L Okun
Jan 5, 2011·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Nadav SchwartzIlan E Timor-Tritsch
Jun 15, 2010·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Sharon M CooleyPeter C Hindmarsh
Aug 21, 2020·Scientific Reports·Soo-Young OhCheong-Rae Roh
Feb 15, 2005·Prenatal Diagnosis

❮ Previous
Next ❯

Related Concepts

Related Feeds

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

Related Papers

Clinica Chimica Acta; International Journal of Clinical Chemistry
Eva M L SmetsCees B M Oudejans
Journal of the Society for Gynecologic Investigation
S W KaumaS W Walsh
© 2021 Meta ULC. All rights reserved