PMID: 18406244Apr 15, 2008Paper

Markers of abdominal adipose tissue in women: relationship to ovarian function

Trends in Endocrinology and Metabolism : TEM
D DewaillyD Deroubaix-Allard

Abstract

Increased abdominal adipose tissue (AAT) mass, as most reliably measured by waist circumference, in pubescent girls positively correlates with insulinemia, circulating insulin-like growth factor 1, insulin resistance, androgenemia, and both plasma luteinizing hormone and estradiol levels. Because insulin resistance and androgen excess regularly accompany the ovarian changes seen in polycystic ovary syndrome (PCOS), we propose that elevated AAT mass in adolescent girls, acting through an increase in insulin resistance, might make them more prone to the development of full-blown PCOS.

References

Jun 1, 1991·Biology of Reproduction·F H Bronson, J M Manning
Jul 1, 1989·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·M Rebuffé-ScriveP Björntorp
May 28, 1993·Annals of the New York Academy of Sciences·D DewaillyP Fossati
Jan 1, 1996·Pediatric Research·A L SicaP M Gootman
Nov 5, 1997·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·N G Norgan

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Citations

Dec 18, 1998·Journal of Endocrinological Investigation·C Cortet-Rudelli, D Dewailly
Sep 23, 2014·General and Comparative Endocrinology·Ajit SinghAmitabh Krishna
Jan 25, 2007·Reproduction : the Official Journal of the Society for the Study of Fertility·Raj Kamal Srivastava, Amitabh Krishna
Dec 29, 2000·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·M J SoaresG R Collier

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