Markers of anaphylaxis - a systematic review

Advances in Medical Sciences
Maria Magdalena Tomasiak-ŁozowskaAnna Bodzenta-Łukaszyk

Abstract

Anaphylaxis is defined as severe, life-threatening, systemic or general, immediate reaction of hypersensitivity, with repeatable symptoms caused by the dose of stimulus which is well tolerated by healthy persons. The proper diagnosis, immediate treatment and differential diagnosis are crucial for saving patient's life. However, anaphylaxis is relatively frequently misdiagnosed or confused with other clinical entities. Thus, there is a continuous need for identifying detectable markers improving the proper diagnosis of anaphylaxis. Here we presented currently known markers of anaphylaxis and discussed in more detail the most clinically valuable ones: tryptase, platelet activacting factor (PAF), PAF-acethylhydrolase, histamine and its metabolites.

Citations

Jul 22, 2018·Current Opinion in Allergy and Clinical Immunology·Giulia De FeoMassimo Triggiani
May 15, 2018·Nutrients·Alexandros TsouprasIoannis Zabetakis
Apr 24, 2019·Journal of Immunology Research·Ofir Klein, Ronit Sagi-Eisenberg
Nov 28, 2018·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Khac-Dung NguyenHaleh Bagheri
Nov 2, 2020·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Yun-Mi KangHyo-Jin An
Dec 3, 2020·International Journal of Molecular Sciences·Peter ValentDean D Metcalfe
Sep 4, 2020·Allergy·Debra de SilvaUNKNOWN European Academy of Allergy and Clinical Immunology Food Allergy and Anaphylaxis Guidelines Group
Jul 24, 2021·Stem Cell Reports·Nir BujanoverRoi Gazit
Dec 5, 2021·Advances in Therapy·Michael S BlaissJoseph Moellman

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