Markers of arterial stiffness in peripheral arterial disease

VASA. Zeitschrift für Gefässkrankheiten
Marc HusmannBeatrice R Amann-Vesti

Abstract

Increased arterial stiffness results from reduced elasticity of the arterial wall and is an independent predictor for cardiovascular risk. The gold standard for assessment of arterial stiffness is the carotid-femoral pulse wave velocity. Other parameters such as central aortic pulse pressure and aortic augmentation index are indirect, surrogate markers of arterial stiffness, but provide additional information on the characteristics of wave reflection. Peripheral arterial disease (PAD) is characterised by its association with systolic hypertension, increased arterial stiffness, disturbed wave reflexion and prognosis depending on ankle-brachial pressure index. This review summarises the physiology of pulse wave propagation and reflection and its changes due to aging and atherosclerosis. We discuss different non-invasive assessment techniques and highlight the importance of the understanding of arterial pulse wave analysis for each vascular specialist and primary care physician alike in the context of PAD.

Citations

Apr 28, 2016·The Canadian Journal of Cardiology·Matthias BartonMatthias R Meyer
Jun 2, 2016·Acta Physiologica·D A ChistiakovY V Bobryshev
Jun 18, 2016·Arteriosclerosis, Thrombosis, and Vascular Biology·Chin Yee Ho, Catherine M Shanahan
May 6, 2019·International Journal of Molecular Sciences·Valentina MercurioFrancesca W Rossi
Nov 13, 2019·Expert Review of Cardiovascular Therapy·Eirini SolomouDimitris Tousoulis
Jul 28, 2019·Journal of Cardiopulmonary Rehabilitation and Prevention·Marilia A CorreiaGabriel G Cucato
Sep 29, 2020·The Journal of Clinical Hypertension·Kevin S TangAnkur D Shah
Jun 27, 2019·Jornal Vascular Brasileiro·Daniel Mendes-Pinto, Maria da Glória Rodrigues-Machado
Feb 19, 2020·Journal of the American Heart Association·Marilia A CorreiaRaphael M Ritti-Dias
Sep 8, 2019·Matrix Biology : Journal of the International Society for Matrix Biology·Wassim FhayliGilles Faury

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