Markers of cellular senescence. Telomere shortening as a marker of cellular senescence

Aging
Alexandra BernadotteIrina M Spivak

Abstract

The cellular senescence definition comes to the fact of cells irreversible proliferation disability. Besides the cell cycle arrest, senescent cells go through some morphological, biochemical, and functional changes which are the signs of cellular senescence. The senescent cells (including replicative senescence and stress-induced premature senescence) of all the tissues look alike. They are metabolically active and possess the set of characteristics in vitro and in vivo, which are known as biomarkers of aging and cellular senescence. Among biomarkers of cellular senescence telomere shortening is a rather elegant frequently used biomarker. Validity of telomere shortening as a marker for cellular senescence is based on theoretical and experimental data.

References

Jul 1, 1996·Experimental Gerontology·A M Olovnikov
Apr 16, 1998·The Journal of Biological Chemistry·E P RogakouW M Bonner
Aug 14, 1998·Human Genetics·K YoungrenA Aviv
Jul 27, 2001·Mechanisms of Ageing and Development·V M Mikhelson
Nov 19, 2002·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Abraham Aviv
Mar 5, 2003·Medical Hypotheses·Stanislaw R Burzynski
Feb 3, 2004·Nature Cell Biology·Olga A SedelnikovaJ Carl Barrett
Apr 7, 2004·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Simon R W L Chan, Elizabeth H Blackburn
Feb 3, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Rafael RamírezPedro Aljama
Apr 12, 2005·Cardiovascular Research·María Dolores Edo, Vicente Andrés
Jul 12, 2005·Analytical Biochemistry·Ronald K Gary, Susan M Kindell
Nov 22, 2005·Psychoneuroendocrinology·Elissa S EpelElizabeth H Blackburn
Dec 24, 2005·Blood Purification·Mark C BoxallThomas von Zglinicki
Apr 22, 2006·Aging Cell·Bo Yun LeeEun Seong Hwang
Jul 19, 2006·Proceedings of the National Academy of Sciences of the United States of America·Sepideh BagheriMohammed Kashani-Sabet
Jan 24, 2007·Molecular and Cellular Biology·Rugang ZhangPeter D Adams
Jul 12, 2007·Proceedings of the National Academy of Sciences of the United States of America·Omer T NjajouWen-Chi Hsueh
Nov 17, 2007·Aging Cell·Olga A SedelnikovaWilliam M Bonner
Sep 23, 2008·Biochemical and Biophysical Research Communications·Kuniyoshi IwabuchiTakayasu Date
Nov 13, 2008·Cell Cycle·Kathleen A Wilson, David F Stern
Feb 14, 2009·Experimental Hematology·Igor SidorovAbraham Aviv
Feb 2, 2010·Experimental Gerontology·Conor LawlessJoão F Passos
Dec 24, 2010·Aging Cell·Jill A KreilingJohn M Sedivy
Feb 4, 2011·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Annette L FitzpatrickAbraham Aviv
Feb 22, 2011·Nature Cell Biology·Raffaella Di MiccoFabrizio d'Adda di Fagagna
Mar 15, 2011·Nature Structural & Molecular Biology·Jasmine S SmithF Brad Johnson
Jul 2, 2011·PloS One·Ulrika SvensonGöran Roos
Oct 22, 2011·Seminars in Cancer Biology·Jerry W Shay, Woodring E Wright
Dec 14, 2011·EMBO Reports·Zeenia KaulRoger R Reddel
Jan 11, 2012·Proceedings of the National Academy of Sciences of the United States of America·Britt J HeidingerPat Monaghan
Sep 12, 2012·Nature Reviews. Genetics·Mary Armanios, Elizabeth H Blackburn

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Citations

Jul 1, 2016·Cell Death & Disease·A GarufiG D'Orazi
Mar 31, 2017·Biogerontology·Daniella Duque-Guimarães, Susan Ozanne
Feb 9, 2018·Molecular Cytogenetics·Nataliya HuleyukMiroslaw Tyrka
Oct 10, 2018·Reproductive Sciences·Luis Alejandro Arias-Sosa
Dec 28, 2018·Drug and Chemical Toxicology·Yuanyuan XiaoFang Xiao
Jul 4, 2019·International Journal of Molecular Sciences·Huda Adwan ShekhidemGil Atzmon
Feb 29, 2020·Journal of Neuroscience Research·Cheryl S Rosenfeld
Mar 19, 2020·Environmental Health Perspectives·Charles W Schmidt
Apr 2, 2020·Nucleic Acids Research·Susanna StroikEric A Hendrickson
Jun 9, 2020·Frontiers in Medicine·Kenneth P HoughVictor J Thannickal
Jul 30, 2020·International Journal of Environmental Health Research·B HermanovaR J Sram
Sep 8, 2016·Journal of Experimental & Clinical Cancer Research : CR·Alessia GarufiGabriella D'Orazi
Oct 19, 2016·Molecular Biology Reports·Menderes Yusuf TerziBulent Gogebakan
Sep 7, 2017·Oxidative Medicine and Cellular Longevity·Arthur José Pontes Oliveira de AlmeidaIsac Almeida de Medeiros
Aug 15, 2017·Oxidative Medicine and Cellular Longevity·Yiru XiaRong Shu
Sep 14, 2017·Journal of Assisted Reproduction and Genetics·Tal Biron-ShentalArie Berkovitch
Jul 6, 2018·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Jane L Tarry-AdkinsSusan E Ozanne
Aug 22, 2018·Frontiers in Aging Neuroscience·Elena D OsipovaAlla B Salmina
Nov 6, 2018·Aging·Na Yang, Payel Sen
Sep 6, 2019·Annals of Neurology·Kristen M KryskoJennifer S Graves
Mar 3, 2020·Frontiers in Cell and Developmental Biology·Zhao-Ni WangZhuang-Gui Chen
Oct 31, 2019·The Journal of International Medical Research·Pan LiuLina Ma
Apr 5, 2020·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Cory M DunganCharlotte A Peterson
Sep 10, 2020·Methods and Protocols·Alice BradfieldDharani K Hapangama
Apr 26, 2017·International Journal of Legal Medicine·Ana Belén Márquez-RuizAurora Valenzuela
Aug 11, 2017·International Journal of Molecular Sciences·Weili Xu, Anis Larbi
Feb 12, 2017·Journal of Forensic Sciences·Sophie ColombArnaud Bourdin
Sep 12, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jingang HouChulhee Choi
May 29, 2018·Canadian Respiratory Journal : Journal of the Canadian Thoracic Society·Xiaohui MaLiang Dong
Jan 18, 2018·Biogerontology·Hani AtamnaJoseph M Dhahbi
Aug 6, 2019·Biochemia Medica·Slavica DodigIvan Pavić
Apr 20, 2019·Frontiers in Genetics·Wolfgang Wagner
Feb 19, 2020·International Journal of Epidemiology·Jean Claude DusingizeDavid C Whiteman

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