Marrow transplantation for children with acute leukemia: experience of Pesaro

Acta Haematologica
C GiardiniL Moretti

Abstract

Thirty children aged 1-15 years with acute lymphoblastic leukemia and acute nonlymphoblastic leukemia were transplanted from HLA-matched donors using two different preparative regimens: 18 patients were prepared with cyclophosphamide and total body irradiation (TBI) while 12 patients received busulphan and cyclophosphamide. Fifteen patients survived 7 to 74 months after transplant. The association of busulphan and cyclophosphamide is a well-tolerated preparation for bone marrow transplant in children with eradicating and immunosuppressive efficacy comparable to that of the well-experienced TBI-cyclophosphamide association.

Citations

Dec 17, 2009·The Cancer Journal·Qing Yi
Jan 1, 1990·Journal of Inherited Metabolic Disease·J R Hobbs

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