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Masking and unmasking of the sialic acid-binding lectin activity of CD22 (Siglec-2) on B lymphocytes

Proceedings of the National Academy of Sciences of the United States of America

Jun 24, 1998

N Razi, Ajit Varki

PMID: 9636173

Abstract

CD22 is a B cell-restricted glycoprotein involved in signal transduction and modulation of cellular activation. It is also an I-type lectin (now designated Siglec-2), whose extracellular domain can specifically recognize alpha2-6-linked sialic acid (Sia) residues. This activity is postu...read more

Mentioned in this Paper

CD22 antigen
Leukocyte Differentiation Antigens, Human
Proteins, Recombinant DNA
Chinese Hamster Ovary Cell
B-Lymphocytes
Plasma Cell Antigens PC-1
Epstein-Barr Virus
B-Cell Lymphomas
Cell Transformation, Viral
Animal Lectins
52
Paper Details
References
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  • Citations105
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Masking and unmasking of the sialic acid-binding lectin activity of CD22 (Siglec-2) on B lymphocytes

Proceedings of the National Academy of Sciences of the United States of America

Jun 24, 1998

N Razi, Ajit Varki

PMID: 9636173

DOI:

Abstract

CD22 is a B cell-restricted glycoprotein involved in signal transduction and modulation of cellular activation. It is also an I-type lectin (now designated Siglec-2), whose extracellular domain can specifically recognize alpha2-6-linked sialic acid (Sia) residues. This activity is postu...read more

Mentioned in this Paper

CD22 antigen
Leukocyte Differentiation Antigens, Human
Proteins, Recombinant DNA
Chinese Hamster Ovary Cell
B-Lymphocytes
Plasma Cell Antigens PC-1
Epstein-Barr Virus
B-Cell Lymphomas
Cell Transformation, Viral
Animal Lectins
52

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Lymphoma, B-Cell

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Related Papers

Paper Details
References
  • References41
  • Citations105
12345
  • References41
  • Citations105
12345...
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