PMID: 8600113Sep 1, 1995Paper

Masking of auditory brainstem responses in young and aged gerbils

Hearing Research
F BoettcherR A Schmiedt

Abstract

Auditory brainstem responses (ABR) were recorded in the presence of low-pass (1 kHz cutoff) or high-pass (8 kHz cutoff) filtered noise in young (4-8 month) and aged (36 month) gerbils. For low-pass maskers, aged gerbils had higher masked thresholds at 2 and 4 kHz than young subjects. This was true for all aged subjects, including those with quiet thresholds similar to those of young controls. For high-pass masking, the majority of aged subjects had higher masked thresholds at 2 and 4 kHz than young controls; however, aged subjects with relatively normal quiet thresholds had masked thresholds similar to those of young subjects. A modified power-law (MPL) model was used to predict masked thresholds for aged subjects. Thresholds measured in the presence of low-pass noise were higher than predicted in many of the aged subjects, particularly those with near-normal quiet thresholds. In contrast, thresholds measured in the presence of the high-pass masker were similar to the predicted thresholds. These results suggest that: (a) excess masking occurred in aged subjects for low-pass, but not high-pass, maskers; (b) the excess masking occurred independently of quiet thresholds; and (c) excess upward spread of masking was related to the s...Continue Reading

References

Oct 1, 1979·The Journal of the Acoustical Society of America·H O'Malley, L L Feth
Aug 1, 1992·Current Opinion in Neurobiology·M A Ruggero
Apr 1, 1992·The Journal of the Acoustical Society of America·J R Dubno, A B Schaefer
Dec 1, 1990·Hearing Research·L I Hellstrom, R A Schmiedt
Mar 1, 1990·The Journal of the Acoustical Society of America·A J KleinW Y Adkins
Jul 1, 1990·Hearing Research·J H MillsL F Kulish
May 1, 1989·Electroencephalography and Clinical Neurophysiology·D I Smith, J H Mills
Mar 1, 1989·The Journal of the Acoustical Society of America·L E Humes, W Jesteadt
Jan 1, 1988·The Journal of the Acoustical Society of America·L E HumesC S Watson
Jun 1, 1988·The Journal of the Acoustical Society of America·J P Gagné
Jan 1, 1986·Audiology : Official Organ of the International Society of Audiology·D E Trees, C W Turner
Jun 1, 1970·Journal of Speech and Hearing Research·E S Martin, J M Pickett
Nov 1, 1984·The Journal of the Acoustical Society of America·R A Schmiedt
Apr 1, 1983·Hearing Research·R J SalviD Henderson
Jul 1, 1982·The Journal of the Acoustical Society of America·P M SellickB M Johnstone
Dec 1, 1982·The Journal of the Acoustical Society of America·R D PattersonR Milroy
Dec 1, 1993·Hearing Research·F A BoettcherR A Schmiedt

❮ Previous
Next ❯

Citations

Sep 2, 2010·Purinergic Signalling·Ravindra S TelangPeter R Thorne
Nov 5, 1997·Hearing Research·S L McFaddenD Henderson
Nov 14, 2012·The Journal of the Acoustical Society of America·Mark E ChertoffJanna L Sorensen
Mar 7, 2014·Cochlear Implants International·D DouchementC Vincent
Apr 4, 2006·Neurobiology of Aging·Lukas RüttigerMarlies Knipper
Oct 24, 2002·Neuroreport·Kelly L TremblayPamela Souza
Jan 28, 2003·Journal of Speech, Language, and Hearing Research : JSLHR·Flint A Boettcher

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.