Abstract
According to sick lobe theory, one or more lobes of the breast are more prone to the development of carcinoma. However, the implications of this theory in breast magnetic resonance imaging (MRI) are unknown. To evaluate the MRI appearance of mass type (multifocal and multicentric diseases) and non-mass type (non-mass enhancements) sick lobe patterns, together with the histopathology results. MRI reports of 2015 patients in two tertiary breast imaging centers between June 2012 and June 2018 were retrospectively reviewed for multifocal-multicentric diseases and segmental, linear, and regional enhancements. A total of 113 patients were included. The specimens obtained by thick needle, vacuum, excisional biopsy/lumpectomy or mastectomy after breast MRI scans were pathologically assessed. The pathologic results were categorized as invasive carcinoma, precursor, and benign proliferative lesions according to the 2012 World Health Organization Classification of Tumors. The percentage of underlying benign and precursor invasive lesions was significantly different in patients with mass and non-mass MRI patterns. While the pathology results of mass type patterns were premalignant and malignant in all cases, nearly half of the underlying h...Continue Reading
References
Sep 1, 1985·Cancer·R HollandJ H Hendriks
Jan 1, 1980·Pathology, Research and Practice·S R Wellings
Mar 15, 1982·Cancer·R L Egan
Dec 2, 1999·Radiology·U FischerE Grabbe
Jun 14, 2000·Breast Cancer Research and Treatment·G AmanoS Satomi
Jul 31, 2002·Radiology·Woo Kyung MoonJung-Gi Im
Nov 15, 2003·European Radiology·M Van GoethemA De Schepper
Sep 24, 2004·AJR. American Journal of Roentgenology·Francesco SardanelliUNKNOWN Italian Trial for Breast MR in Multifocal/Multicentric Cancer
Jun 1, 2005·Virchows Archiv : an International Journal of Pathology·Tibor Tot
Jun 23, 2006·Breast Cancer Research and Treatment·James J Going, Timothy J Mohun
Aug 2, 2006·Breast Cancer Research : BCR·James J Going
Oct 5, 2007·International Journal of Surgical Pathology·Tibor Tot
Oct 13, 2007·Cancer·Tibor Tot
Oct 26, 2007·The Breast : Official Journal of the European Society of Mastology·C KuhlH Schild
May 13, 2008·Journal of the American College of Surgeons·Stephen R GrobmyerWilliam G Cance
Sep 19, 2008·Human Pathology·Tibor Tot
Jul 22, 2009·Virchows Archiv : an International Journal of Pathology·Tibor TotMiklós Tarján
Apr 13, 2010·The Breast : Official Journal of the European Society of Mastology·Tibor Tot
Jun 15, 2011·Human Pathology·Tibor TotLászló Tabár
Feb 2, 2012·International Journal of Breast Cancer·Tibor Tot
Nov 3, 2012·International Journal of Breast Cancer·Julio A Ibarra
Nov 15, 2012·International Journal of Breast Cancer·Tibor Tot
Jan 15, 2013·International Journal of Breast Cancer·F Lee Tucker
Sep 13, 2013·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Catherine S GiessRobyn L Birdwell
Dec 11, 2013·Medical Physics·E E FowlerJ J Heine
Nov 19, 2015·Journal of Medical Ultrasonics·Dominique AmyTibor Tot
Aug 24, 2017·The Breast Journal·Mona P TanTibor Tot
Jan 29, 2019·Gland Surgery·Mona P Tan, Tibor Tot
Jul 31, 2019·Radiology·Ritse M MannLinda Moy