Mass flow of antibiotics in a wastewater treatment plant focusing on removal variations due to operational parameters

The Science of the Total Environment
Conrad MarxVolker Kuehn

Abstract

Wastewater treatment plants (WWTPs) are not designed to purposefully eliminate antibiotics and therefore many previous investigations have been carried out to assess their fate in biological wastewater treatment processes. In order to consolidate previous findings regarding influencing factors like the solid and hydraulic retention time an intensive monitoring was carried out in a municipal WWTP in Germany. Over a period of 12months daily samples were taken from the in- and effluent as well as diverse sludge streams. The 14 selected antibiotics and one metabolite cover the following classes: cephalosporins, diaminopyrimidines, fluoroquinolones, lincosamide, macrolides, penicillins, sulfonamides and tetracyclines. Out of the 15 investigated substances, the removal of only clindamycin and ciprofloxacin show significant correlations to SRT, temperature, HRT and nitrogen removal. The dependency of clindamycin's removal could be related to the significant negative removal (i.e. production) of clindamycin in the treatment process and was corrected using the human metabolite clindamycin-sulfoxide. The average elimination was adjusted from -225% to 3% which suggests that clindamycin can be considered as an inert substance during the wa...Continue Reading

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Oct 26, 2016·Environmental Toxicology and Chemistry·Nicol JaneckoIvan Literak
Aug 21, 2016·The Science of the Total Environment·Johan Bengtsson-PalmeD G Joakim Larsson
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Sep 3, 2021·Chemical & Pharmaceutical Bulletin·Toshinari SuzukiTetsuji Nishimura

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