PMID: 9178807May 16, 1997Paper

Mass screening for neuroblastoma and mortality in birth cohorts

International Journal of Cancer. Journal International Du Cancer
M NishiN Takasugi

Abstract

Mortality resulting from neuroblastoma in birth cohorts in both Sapporo City and the whole of Japan was investigated to evaluate the effects of a high-performance liquid chromatography (HPLC) mass screening program, targeting on 6 month-old infants. In Sapporo City, the non-HPLC screened cohort showed no reduction in mortality at 4 years of age compared with the pre-screening cohort. However, the HPLC screened cohort showed a reduction of 69% in mortality compared with the pre-screening cohort. On a nation-wide scale, there was a significant decline in mortality for the non-HPLC screened cohort compared with the pre-screening cohort; for the HPLC screened cohort for 1989-1991, there was also a reduction in mortality for children younger than 2 years of age. The incidence of neuroblastoma at 1-4 years of age in the HPLC cohort in Sapporo City was about half that in the pre-screening cohort, along with and probably because of an increasing incidence among infants in the same cohort. Our findings suggest that HPLC screening may detect some poor-prognosis neuroblastoma cases at early stages, thus providing for more favorable therapy.

References

Nov 1, 1992·The American Journal of Pediatric Hematology/oncology·M NishiN Takasugi
Jan 1, 1990·Medical and Pediatric Oncology·Y HanawaA Tsunoda

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Citations

Apr 5, 2002·The New England Journal of Medicine·Freimut H SchillingJoerg Michaelis
May 7, 2004·The New England Journal of Medicine·Yoshitaka Tsubono, Shigeru Hisamichi
Dec 18, 1998·Journal of Pediatric Surgery·S SuitaK Ikeda
Apr 8, 2016·Journal of Epidemiology·Kota Katanoda
Oct 26, 2016·International Journal of Cancer. Journal International Du Cancer·Takafumi ShinagawaTomotaka Sobue
Mar 1, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Keiko YamamotoMasako Tanimura
Jan 4, 2020·European Journal of Pediatrics·Ruben Van PaemelBram De Wilde
Jul 29, 1998·Medical and Pediatric Oncology·F Bessho
Dec 28, 1999·Medical and Pediatric Oncology·Y TsuchidaM Tanimura

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