Abstract
Sulfur mustards are a class of vesicant chemical warfare agents that rapidly degrade in environmental samples. The most feasible degradation products of sulfur mustards are chloroethyl vinylic compounds and divinylic compounds, which are formed by the elimination of one and two HCl molecules from sulfur mustards, respectively. The detection and characterization of these degradation products in environmental samples are an important proof for the verification of sulfur mustard usage. In this study, we synthesized a set of sulfur mustard degradation products, i.e., divinylic compounds (1-7) and chloroethyl vinylic compounds (8-14), and characterized using gas chromatography/mass spectrometry (GC/MS) under electron ionization (EI) and chemical ionization (CI) (methane) conditions. The EI mass spectra of the studied compounds mainly included the fragment ions that resulted from homolytic cleavages with or without hydrogen migrations. The divinylic compounds (1-7) showed [M-SH](+) ions, whereas the chloroethylvinyl compounds (8-14) showed [M-Cl](+) and [M-CH2CH2Cl](+) ions. Methane/CI mass spectra showed [M+H](+) ions and provided molecular weight information. The GC retention index (RI) values were also calculated for the studied c...Continue Reading
References
Jan 1, 1984·Journal of Cancer Research and Clinical Oncology·P NehlsM F Rajewsky
Feb 25, 1994·Journal of Chromatography. a·R M BlackM T Reid
Mar 1, 1994·Chemical Research in Toxicology·A FidderH P Benschop
Jan 1, 1996·Archives of Toxicology·A FidderA G Hulst
Aug 27, 1998·Journal of Chromatography. a·C E Kientz
Aug 24, 1999·Journal of Chromatography. a·E W HooijschuurU A Brinkman
Mar 28, 2001·Journal of Chromatography. a·U V Vijaya SaradhiB Jayaram
Jul 19, 2001·Journal of Chromatography. a·M MazurekM Sliwakowski
Apr 22, 2004·European Journal of Mass Spectrometry·Paul A D'AgostinoClaude L Chenier
Jul 6, 2004·Journal of Chromatography. a·T Jagadeshwar ReddyM Vairamani
Jul 9, 2004·Journal of Analytical Toxicology·Benedict R CapacioWilliam D Korte
Jun 23, 2006·Rapid Communications in Mass Spectrometry : RCM·V V S LakshmiM Vairamani
Oct 20, 2006·Journal of Hazardous Materials·Carol A S BrevettJeffrey S Rice
Jul 3, 2007·Analytical and Bioanalytical Chemistry·Douglas D Richardson, Joseph A Caruso
Feb 14, 2008·Journal of Analytical Toxicology·J Richard SmithJohn R Barr
Feb 14, 2008·Journal of Analytical Toxicology·Benedict R CapacioAlfred M Sciuto
Jun 1, 2013·Rapid Communications in Mass Spectrometry : RCM·R KarthikrajM Vairamani
Citations
Nov 9, 2019·European Journal of Mass Spectrometry·A VeereshamS Prabhakar
May 23, 2018·Talanta·Karin Höjer HolmgrenDaniel Wiktelius
Jun 5, 2020·Analytical Chemistry·Meijuan ZhangJianwei Xie
Sep 20, 2018·The Journal of Organic Chemistry·Esther Gómez-CaballeroMiguel A Sierra