PMID: 1204134Nov 1, 1975Paper

Mass spectrometric analysis of permethylated glycosphingolipids I. Sequence analysis of two blood-group B active glycosphingolipids from human B erythrocyte membranes

Chemistry and Physics of Lipids
P Hanfland, H Egge

Abstract

Two blood group B active glycosphingolipids (B-I and B-II) formerly isolated and purified from human B erythrocytes (16) were investigated by mass spectrometry after permethylation. B-I yielded fragments up to m/e 1266 and B-II up to m/e 1495, showing the sequence of six and seven carbohydrate residues respectively. In combination with additional experimental evidence (18) the glycosphingolipids are demonstrated to be a gal-[ fuc ]-gal-glcNAc-gal-glc-ceramide (B-I) and a gal-[ fuc ]-gal-glcNAc-gal-glcNAc-gal-glc-ceramide (B-II). Mass spectrometric evidence for the ceramide residues are also obtained indicating besides spingosine C24-,C24:1-, and C22-fatty acids as main constituents.

References

Nov 1, 1972·Chemistry and Physics of Lipids·K A KarlssonG O Steen
May 1, 1974·Chemistry and Physics of Lipids·S P Markey, D A Wenger
Feb 1, 1974·Biomedical Mass Spectrometry·K A KarlssonB E Samuelsson
Dec 1, 1974·Chemistry and Physics of Lipids·R W LedeenJ W Fong
Nov 15, 1972·Biochemical and Biophysical Research Communications·S HakomoriK Watanabe
Jan 1, 1973·Hoppe-Seyler's Zeitschrift für physiologische Chemie·W Stoffel, P Hanfland
Oct 1, 1970·Chemistry and Physics of Lipids·K Samuelsson, B Sameulsson
Oct 1, 1972·Chemistry and Physics of Lipids·B A AnderssonG O Steen
Sep 24, 1969·Biochemical and Biophysical Research Communications·K A KarlssonG O Steen
Sep 24, 1969·Biochemical and Biophysical Research Communications·C C Sweeley, G Dawson
Jun 19, 2007·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Jens VoortmanGiuseppe Giaccone

❮ Previous
Next ❯

Citations

Jun 1, 1980·Chemistry and Physics of Lipids·R Gigg

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.