PMID: 3756182Sep 26, 1986Paper

Mass spectrometric detection of the plasma prealbumin (transthyretin) variant associated with familial amyloidotic polyneuropathy

Biochimica Et Biophysica Acta
Y WadaA Hayashi

Abstract

A plasma prealbumin variant with a methionine-for-valine substitution at position 30 is closely associated with familial amyloidotic polyneuropathy (FAP) type I. Secondary ion mass spectrometry of the tryptic digest of a carrier's prealbumin could easily detect an abnormal peptide containing the substitution besides the normal peptide. This is a sensitive and reliable method for the diagnosis of FAP.

References

Jan 12, 1985·Lancet·M NakazatoH Matsuo
Jul 31, 1984·Biochemical and Biophysical Research Communications·M NakazatoS Araki
Aug 1, 1984·Biomedical Mass Spectrometry·I KatakuseA Hayashi
Feb 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·F E Dwulet, M D Benson

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Citations

Sep 27, 2003·Biochemical and Biophysical Research Communications·Jörn Oliver SassAkira Shimizu
Jun 21, 2012·The International Journal of Biochemistry & Cell Biology·Gaetano InvernizziSalvador Ventura
Jan 1, 1988·Scandinavian Journal of Immunology·M NordlieP J Ranløv
Jun 26, 2004·Clinical Chemistry·H Robert BergenDavid C Muddiman
Dec 3, 2003·Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis·H Robert BergenStephen Naylor
Feb 3, 2007·Journal of Proteome Research·Jolein GloerichLambert P van den Heuvel

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