Mass spectrometric map of neuropeptide expression and analysis of the gamma-prepro-tachykinin gene expression in the medaka (Oryzias latipes) brain

General and Comparative Endocrinology
Yuji SuehiroHideaki Takeuchi

Abstract

Neuropeptides have important roles in modulating behavioral patterns such as social interaction. With the aim to determine the presence of neuropeptides known to be involved in social interaction as well as novel peptides, we used MALDI-TOF/MS to analyze neuropeptide profiles in some medaka brain regions. In the telencephalon, hypothalamus, and pituitary gland, 3, 6, and 10 peaks, respectively, were identified as neuropeptides (Arg-vasotocin [AVT], growth hormone-releasing hormone [GHRH], neuropeptide FF, substance P [SP], somatostatin-1 and -2, melanin-concentrating hormone [MCH], MCH gene-related peptide [Mgrp], melanocyte-stimulating hormone [MSH], corticotropin-like intermediate lobe peptide [CLIP], and beta-endorphin). The neuropeptide profile of telencephalon similar to that of the hypothalamus, but completely different from that of pituitary gland. For the future genetic analysis, we identified cDNAs encoding precursor proteins for the identified peptides. We also detect its expression of gamma-prepro-tachykinin gene encoding a SP precursor protein in both the telencephalon and hypothalamus. Our results indicated that the medaka brain contains some neuropeptides (AVT, SP, and somatostatins) that may be involved in modula...Continue Reading

References

Jan 1, 1989·The Journal of Comparative Neurology·S C SharmaR Breckwoldt
Mar 10, 2001·Current Opinion in Neurobiology·T R Insel, L J Young
Jun 26, 2001·Brain Research. Brain Research Reviews·J L Goodson, A H Bass
Mar 30, 2002·Brain Research Bulletin·Matthew S GroberRui F Oliveira
May 31, 2002·Pharmacological Reviews·Cinzia SeveriniVittorio Erspamer
Mar 5, 2004·Cell and Tissue Research·Hideaki TakeuchiTakeo Kubo
Apr 15, 2004·Current Opinion in Neurobiology·James T Winslow, Thomas R Insel
Jun 24, 2004·Mechanisms of Development·Makoto Furutani-Seiki, Joachim Wittbrodt
Oct 1, 2004·The Journal of Comparative Neurology·François AuclairRéjean Dubuc
May 12, 2005·Hormones and Behavior·James L Goodson
Aug 5, 2006·Endocrinology·Brian C Trainor, Hans A Hofmann
Dec 13, 2006·Genome Biology·Yoshihito TaniguchiEdwin Cuppen
Mar 29, 2007·Brain, Behavior and Evolution·Alexander A PollenHans A Hofmann
Apr 24, 2007·Nature Genetics·Herman A Dierick, Ralph J Greenspan
Mar 21, 2008·Molecular BioSystems·Hanife Esengil, James K Chen
Apr 22, 2008·Development, Growth & Differentiation·Shuhei NakamuraMinoru Tanaka

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Citations

Jun 12, 2012·Progress in Neurobiology·Ishwar ParharTakashi Kitahashi
Dec 3, 2011·General and Comparative Endocrinology·Akikazu YasudaYasushi Shigeri
Feb 23, 2019·Pigment Cell & Melanoma Research·Gabriel E BertolesiSarah McFarlane
Mar 21, 2012·The Journal of Comparative Neurology·Satoshi OgawaIshwar S Parhar

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