PMID: 8588961Jan 1, 1995Paper

Massive intercalary bone allografts in the treatment of primary and secondary bone tumors. A report on 21 cases

Archives of Orthopaedic and Trauma Surgery
G VoggenreiterK P Schmit-Neuerburg

Abstract

From 1981 to 1993, 21 patients received intercalary bone allografts for reconstruction of the extremity after en bloc tumor resection (15 malignant and 6 benign tumors). The allografts were collected from multiorgan donors and cryopreserved at -70 degrees C. The mean follow-up was 4.4 (range 1-13) years. The fate of the grafts was followed by conventional radiography, bone scintigraphy, and functional assessment. The overall survival rate of the 7 patients with high-grade malignancies was 86%. Solid union of the graft-host sites in less that 15 months occurred in 85%. An increased isotope uptake of the graft indicates that incorporation at the osteotomies as well as remodelling is still continuing at 9 years after operation. The overall complication rate was 43%; 3 patients had two or more complications. Complications were related to the allograft in 6 (infection or fatigue fracture in 1 and delayed healing in 4 cases) and to the osteosynthesis in 3 patients. The definitive results after treatment of complications show that satisfactory results have been obtained in all but 2 patients: 62% had excellent, 19% good, and 10% fair results. Intercalary allografts therefore provide a valuable solution for large skeletal defects after...Continue Reading

References

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Citations

Apr 5, 2002·Plastic and Reconstructive Surgery·Dimitrios P MastorakosPeter G Cordeiro
Nov 14, 2013·The Journal of Craniofacial Surgery·Hasan Ikbal AtilganDuygu Kankaya
Oct 28, 2006·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·G Elizabeth PluharMark D Markel
Feb 11, 2010·Clinical Orthopaedics and Related Research·Benjamin J Miller, Walter W Virkus
Mar 16, 2007·The Journal of Bone and Joint Surgery. British Volume·A H KriegP D Stalley
Feb 1, 1997·Acta Orthopaedica Scandinavica. Supplementum·P F Choong

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