PMID: 9170369May 1, 1997Paper

Massive osteolysis after ceramic on ceramic total hip arthroplasty. A case report

Clinical Orthopaedics and Related Research
P Z Wirganowicz, B J Thomas

Abstract

The case of a 66-year-old woman who sustained a pathologic femur fracture secondary to extensive osteolysis distal to a pressfit femoral prosthesis with a ceramic on ceramic bearing surface is reported. The femoral and acetabular bearing surfaces showed signs of visible wear, although the stem showed little evidence of burnishing. Material curetted from the femoral medullary canal in the area of the osteolysis contained extensive amounts of histiocytes and foreign body debris. Qualitative spectrographic analysis of the curetted material showed levels of aluminum to be approximately 10 times more prevalent than either cobalt or chromium. Although there is little understanding of the cellular reactions to ceramic debris products, the extensive osteolysis seen in this patient suggests that alumina ceramic bearings may not be as biologically inert as initially perceived.

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Citations

May 13, 1999·Journal of Biomedical Materials Research·T KuboY Hirasawa
Jan 5, 2002·Clinical Orthopaedics and Related Research·P BizotL Sedel
Jan 22, 2005·Clinical Orthopaedics and Related Research·Didier HannoucheLaurent Sedel
Mar 3, 2005·The Journal of Bone and Joint Surgery. American Volume·Young-Hoo KimCath Hardaker
Aug 1, 2014·Clinical Orthopaedics and Related Research·Thomas W BauerUNKNOWN Biological Working Group
Aug 15, 2001·Clinical Orthopaedics and Related Research·Y MochidaT W Bauer
Dec 7, 2007·The Journal of Bone and Joint Surgery. American Volume·P J LustyB A Zicat
Mar 22, 2012·The Journal of Bone and Joint Surgery. British Volume·P Whittingham-JonesJ A Skinner
May 18, 2000·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·S Y KwonK L Sung
Mar 16, 2000·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·E Ingham, J Fisher
Feb 13, 2004·The Journal of Bone and Joint Surgery. American Volume·Jeong Joon YooYoung-Min Kim
Sep 15, 2007·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Chong Bum ChangHee Joong Kim
Sep 25, 1999·Journal of Biomedical Materials Research·Y JossetD Laurent-Maquin
Dec 28, 1999·Clinical Orthopaedics and Related Research·H B Skinner
Dec 4, 2002·Clinical Orthopaedics and Related Research·Benjamin E BierbaumDaniel Ward
Jun 2, 2011·Expert Review of Medical Devices·Michael G ZywielMichael A Mont
Feb 22, 2008·Clinical Orthopaedics and Related Research·Kentaro IwakiriKunio Takaoka
Oct 20, 2000·Clinical Orthopaedics and Related Research·M J ArchibeckJ Black
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Dec 4, 2004·Clinical Orthopaedics and Related Research·Robert L BarrackHarry B Skinner
Jun 8, 2011·Nanomedicine : Nanotechnology, Biology, and Medicine·Y F ZhangL Qin

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