PMID: 9633982Jun 20, 1998Paper

Massive subdural haematoma: an unusual complication of septicaemia in preterm very low birthweight infants

Journal of Paediatrics and Child Health
P C NgK L Cheung

Abstract

Non-traumatic massive subdural haematoma is a rare condition in newborn infants and is usually associated with hereditary coagulation disorders or congenital vascular malformation. Its occurrence in preterm very low birthweight infants secondary to systemic bacterial infection has not been reported. We describe two extremely preterm neonates who developed massive subdural haematoma as a result of gram-negative septicaemia and disseminated intravascular coagulation. Both infants suffered severe parenchymal cerebral injury and hydrocephalus. Clinicians should be aware of this unusual and catastrophic complication if a very low birthweight infant with severe sepsis and disseminated intravascular coagulation suddenly deteriorates despite successful treatment with antibiotics. Radiological imaging by cranial ultrasound or computed tomography scanning should be routinely considered in all such infants for the detection of intracranial bleeding.

Citations

Dec 2, 1999·Pediatric Neurology·S Chamnanvanakij, J M Perlman
Oct 1, 2008·Journal of Indian Association of Pediatric Surgeons·Manjiri SomashekharMugdha Wakodkar
Feb 13, 2003·Neuropathology and Applied Neurobiology·J F GeddesI Scheimberg
Jul 6, 2000·The Pediatric Infectious Disease Journal·M J Abzug, S M Johnson
Jan 15, 2019·Expert Review of Anti-infective Therapy·Ying DongChristian P Speer

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