PMID: 8583599Mar 1, 1996Paper

Mast cell counts are not useful in the diagnosis of nonulcerative interstitial cystitis

The Journal of Urology
P A DundoreH Semerjian

Abstract

Mast cell counts have been advocated as useful in the pathological diagnosis of interstitial cystitis. To determine the clinical significance of mucosal and detrusor muscle mast cells we quantified mast cells within the lamina propria and detrusor muscle in nonulcerative interstitial cystitis, and various inflammatory and neoplastic bladder diseases. Mast cells from Giemsa stained sections were enumerated from 8 cases of clinically diagnosed nonulcerated interstitial cystitis and 32 control cases having inflammatory or neoplastic bladder disease. Cystectomy specimens from controls also included sections from normal (5) and inflamed transitional mucosa (4) distant from the invasive tumor. There was no significant difference in mast cell counts when considered absolutely or relative to the muscle-to-mucosa ratio in cases of nonulcerative interstitial cystitis and controls. Our findings indicate that mast cell counts are not useful in the evaluation of nonulcerative interstitial cystitis and do not represent a diagnostic criterion for inclusion or exclusion of the disease.

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Citations

May 30, 2001·Urology·J E TomaszewskiUNKNOWN Interstitial Cystitis Database Study Group
Sep 8, 2000·International Journal of Urology : Official Journal of the Japanese Urological Association·T YamadaK Akiyama
Jun 18, 1998·Annals of the New York Academy of Sciences·T C TheoharidesG R Sant
Sep 8, 2009·European Urology·Magnus FallUNKNOWN European Association of Urology
Oct 31, 2008·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·P MouracadeC Saussine
May 23, 2012·Scandinavian Journal of Urology and Nephrology·Yr LogadottirRalph Peeker
Oct 25, 2017·Neurourology and Urodynamics·Yoshiyuki AkiyamaYukio Homma
Feb 16, 2005·The Journal of Urology·Frédéric Soucy, Mireille Grégoire
Jun 25, 2009·International Journal of Urology : Official Journal of the Japanese Urological Association·Yukio HommaUNKNOWN Interstitial cystitis guideline committee
Jan 6, 2009·International Journal of Urology : Official Journal of the Japanese Urological Association·Yukio HommaHikaru Tomoe
Jun 11, 2011·Neurourology and Urodynamics·Dale E BjorlingWade Bushman

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