Mastectomy and immediate breast reconstruction in the elderly: Trends and outcomes

Surgery
Alaa SadaTina J Hieken

Abstract

Immediate breast reconstruction after mastectomy may confer more complication rates in the elderly. Therefore, granular analysis of postmastectomy complications in women aged ≥65 years may help formulate clinical guidelines to improve patient selection and outcomes. We identified patients undergoing mastectomy with or without immediate reconstruction from our breast surgery database (2014-2018). Complications requiring treatment were compared between patients aged ≥65 and <65 years. A total of 1,721 mastectomies were performed in 1,698 patients; 85.8% had a 30-day follow-up. Of these patients, 968 (65.6%) had immediate breast reconstruction, of whom 95 (9.8%) were aged ≥65 years. Among patients aged ≥65 years, 27.6% underwent mastectomy with immediate breast reconstruction compared with 77.1% of women aged <65 years (P < .001). Overall complication rates were not greater for older compared with younger mastectomy patients but were for older versus younger patients who had mastectomy with immediate breast reconstruction (12.6% vs 6.8%; P = .04). Hematoma requiring reoperation was more frequent in patients aged ≥65 years (5.3% vs 0.9%; P = .006). Necrosis (5.3% vs 2.6%; P = .18) and 30-day unplanned readmissions (7.4% vs 4.0%; P ...Continue Reading

References

Jun 30, 2000·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·C M ContantT Wiggers
Jun 2, 2005·The Breast : Official Journal of the European Society of Mastology·Elisabeth Edström ElderKerstin Sandelin
Apr 5, 2008·Journal of the American College of Surgeons·Caprice C GreenbergKatherine L Kahn
Mar 5, 2011·Cancer Treatment Reviews·Lauren WaltonRiccardo A Audisio
Jan 26, 2012·The American Surgeon·Marissa Howard-McNattLisa David
Mar 1, 2012·Plastic and Reconstructive Surgery·James B Collins, Charles N Verheyden
Dec 25, 2012·Annals of Surgical Oncology·Haejin InCaprice C Greenberg
Mar 1, 2011·Geriatric Orthopaedic Surgery & Rehabilitation·Relin YangMichael C Lewis
Jun 14, 2013·International Journal of Clinical Practice·R SinhaA Ring
Oct 1, 2013·Journal of the American College of Surgeons·John P FischerLiza C Wu
Feb 28, 2017·Journal of the American College of Surgeons·Waleed O GibreelTina J Hieken
Jan 10, 2018·CA: a Cancer Journal for Clinicians·Rebecca L SiegelAhmedin Jemal

❮ Previous
Next ❯

Citations

May 27, 2020·The Breast Journal·Carmen LeserChristian Singer
Jun 13, 2020·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Teresa PaolucciMassimiliano Mangone
Jan 11, 2021·Breast Cancer Research and Treatment·Neda StjepanovicUNKNOWN Hereditary Breast Cancer Clinical Study Group
Mar 27, 2021·Frontiers in Surgery·Marco MaterazzoOreste Claudio Buonomo
Aug 26, 2021·Journal of Plastic Surgery and Hand Surgery·Barkat AliRohini G McKee

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.