Material matters: Analysis of density uncertainty in 3D printing and its consequences for radiation oncology

Medical Physics
Daniel F CraftRebecca M Howell

Abstract

Using 3D printing to fabricate patient-specific devices such as tissue compensators, boluses, and phantoms is inexpensive and relatively simple. However, most 3D printing materials have not been well characterized, including their radiologic tissue equivalence. The purposes of this study were to (a) determine the variance in Hounsfield Units (HU) for printed objects, (b) determine if HU varies over time, and (c) calculate the clinical dose uncertainty caused by these material variations. For a sample of 10 printed blocks each of PLA, NinjaFlex, ABS, and Cheetah, the average HU and physical density were tracked at initial printing and over the course of 5 weeks, a typical timeframe for a standard course of radiotherapy. After initial printing, half the blocks were stored in open boxes, the other half in sealed bags with desiccant. Variances in HU and density over time were evaluated for the four materials. Various clinical photon and electron beams were used to evaluate potential errors in clinical depth dose as a function of assumptions made during treatment planning. The clinical depth error was defined as the distance between the correctly calculated 90% isodose line and the 90% isodose line calculated using clinically reason...Continue Reading

References

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Sep 1, 2017·Journal of Applied Clinical Medical Physics·Daniel F Craft, Rebecca M Howell

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Citations

Nov 27, 2018·Physics in Medicine and Biology·Nikolai J MickeviciusEric S Paulson
Mar 2, 2019·Journal of Applied Clinical Medical Physics·Garrett C BaltzRebecca M Howell
Apr 26, 2019·Physics in Medicine and Biology·Jong Min ParkJung-In Kim
Oct 2, 2019·Medical Physics·Davide BrivioPiotr Zygmanski
Oct 21, 2018·Radiation Oncology·Giovanna DipasqualeRaymond Miralbell
Aug 28, 2019·Journal of Applied Clinical Medical Physics·David Kiyoshi SasakiArbind Dubey
Sep 14, 2019·Technology in Cancer Research & Treatment·Rance TinoTomas Kron
Jul 1, 2020·3D Printing in Medicine·Ergys SubashiOana Craciunescu
Nov 16, 2019·Australasian Physical & Engineering Sciences in Medicine·Marchant Van der WaltChristine Albantow
Sep 30, 2018·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·Rachel B GerLaurence E Court
May 10, 2021·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Jean-Luc DumasLudovic De Marzi
Sep 17, 2021·Physical and Engineering Sciences in Medicine·T KairnS B Crowe

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