Materials and structures used in meniscus repair and regeneration: a review

BioMedicine
Ketankumar VadodariaPrakash Vasudevan

Abstract

Meniscus is a vital functional unit in knee joint. It acts as a lubricating structure, a nutrient transporting structure, as well as shock absorber during jumping, twisting and running and offers stability within the knee joint. It helps in load distribution, in bearing the tensile hoop stresses and balancing by providing a cushion effect between hard surfaces of two bones. Meniscus may be injured in sports, dancing, accident or any over stressed condition. Any meniscal lesion can lead to a gradual development of osteoarthritis or erosion of bone contact surface due to disturbed load and contact stress distribution caused by injury/pain. Once injured, the possibilities of self-repair are rare in avascular region of meniscus, due to lack of blood supply in avascular region. Meniscus has vascular and avascular regions in structure. Majority of the meniscus parts turn avascular with increase in age. Purpose of this review is to highlight advances in meniscus repair with special focus on tissue engineering using textile/fiber based scaffolds, as well as the recent technical advances in scaffolds for meniscus recon- struction/ regeneration treatment.

References

Jan 1, 1977·Zdravookhranenie Rossiĭskoĭ Federatsii·Iu N Semovskikh, M P Kirilenko
Aug 1, 1984·Annals of the Rheumatic Diseases·J HerwigE Buddecke
Jan 1, 1993·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·D Kohn
Jan 1, 1997·International Orthopaedics·D KohnH Maschek
Jun 13, 1998·Anatomy and Embryology·W Petersen, B Tillmann
Aug 23, 2000·British Journal of Sports Medicine·E Rath, J C Richmond
Feb 17, 2001·Osteoarthritis and Cartilage·M P Hellio Le GraverandD A Hart
May 4, 2001·Journal of Biomaterials Science. Polymer Edition·D W Hutmacher
Nov 10, 2001·Annual Review of Biomedical Engineering·C T LaurencinJ A Cooper
Mar 12, 2002·Tissue Engineering·Chisa HidakaRonald G Crystal
Nov 19, 2003·Journal of Biomedical Materials Research. Part a·Guoping ChenTetsuya Tateishi
Dec 16, 2003·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Nicholas A SgaglioneFreddie H Fu
Dec 31, 2003·Biomaterials·P BumaR P H Veth
Aug 31, 2004·Journal of Materials Science. Materials in Medicine·R G J C HeijkantsR P H Veth
Dec 2, 2004·The American Journal of Sports Medicine·Henning MadryStephen B Trippel
Sep 8, 2005·Tissue Engineering·Adam C Aufderheide, Kyriacos A Athanasiou
Mar 4, 2006·Journal of Biomedical Materials Research. Part a·Sun-Woong KangByung-Soo Kim
May 30, 2006·Osteoarthritis and Cartilage·C ChiariS Nehrer
Jul 18, 2006·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Stefano ZaffagniniMaurilio Marcacci
Oct 27, 2006·The Journal of Orthopaedic and Sports Physical Therapy·Paul B LewisBrian J Cole
Jan 26, 2007·Biomaterials·Brendon M Baker, Robert L Mauck
Mar 3, 2007·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·James H LubowitzRené Verdonk
May 5, 2007·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Kevin R StoneJohn Crues
Oct 14, 2008·Osteoarthritis and Cartilage·B M BakerR L Mauck
Dec 10, 2008·Clinics in Sports Medicine·Tony G van TienenPieter Buma
Mar 11, 2009·Biotechnology and Bioengineering·Najmuddin J Gunja, Kyriacos A Athanasiou
Jun 30, 2009·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Geoffrey S Van ThielBrian Cole
Nov 26, 2009·Journal of Tissue Engineering and Regenerative Medicine·Najmuddin J Gunja, Kyriacos A Athanasiou
Jul 17, 2010·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Gal ZurAvi Shterling
Aug 31, 2010·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Gerjon HanninkPieter Buma
Oct 12, 2010·Biomaterials·Biman B MandalDavid L Kaplan
Oct 25, 2011·Journal of Biomedical Materials Research. Part a·Eric BalintMichael G Dunn
Jun 16, 2012·Acta Biomaterialia·Lara C IonescuRobert L Mauck
Sep 28, 2012·Sports Health·Alice J S FoxScott A Rodeo

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BETA
Scanning electron microscopy

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