With the introduction of screening programmes for haemoglobinopathies (HbP), more women will be aware of their HbP status. The genetic risk for women who are carriers of HbP is well known. However, midwives and obstetricians need to know whether there are other risks involved in the pregnancies of women who are carriers of HbP. The objective of this study was to investigate the hypothesis that being a carrier of HbP has no consequences for the health of pregnant women and the outcome of their pregnancies. A systematic search was carried out until August 2008 in the Cochrane Library, Medline, EMBASE and CINAHL databases. All references were inspected to identify further studies. The authors of key publications were contacted for any unpublished research. Selection of studies was made on the basis of the following criteria: Cohort and case-control studies, pregnant women with a singleton pregnancy, exposure: HbAS or thalassaemia minor and the following outcomes: urinary tract infection (UTI), anaemia, (pre-)eclampsia, gestational diabetes, premature labour, low birth weight, intrauterine growth retardation, miscarriage, neonatal death, low Apgar score, neural tube defects. Quality assessment and data extraction were carried out b...Continue Reading
Evidence for rapid loss of newly synthesized haemoglobin S molecules in sickle cell anaemia and sickle cell trait
The prognostic value of blood glucose and glycosylated haemoglobin estimation in patients with stroke
The effects of maternal sickle cell hemoglobinopathies and sickle cell trait on reproductive performance
Changes in the mean corpuscular red cell volume in women with beta-thalassaemia trait during pregnancy
Why mothers die--report on confidential enquiries into maternal deaths in the United Kingdom 1994-96
Protection afforded by sickle-cell trait (Hb AS): what happens when malarial selection pressures are alleviated?
On the bias produced by quality scores in meta-analysis, and a hierarchical view of proposed solutions
The development, validation and reliability of a nutrition screening tool based on the recommendations of the British Association for Parenteral and Enteral Nutrition (BAPEN)
Pregnancy loss after first-trimester viability in women with sickle cell trait: time for a reappraisal?
Tools for assessing quality and susceptibility to bias in observational studies in epidemiology: a systematic review and annotated bibliography
A study exploring UK midwives' knowledge and attitudes towards caring for women who have been sexually abused
Are pregnant women of non-Northern European descent more anaemic than women of Northern European descent? A study into the prevalence of anaemia in pregnant women in Amsterdam
Severe maternal morbidity during pregnancy, delivery and puerperium in the Netherlands: a nationwide population-based study of 371,000 pregnancies
The role of haemoglobin A(2) testing in the diagnosis of thalassaemias and related haemoglobinopathies
Modern state of acute myocardial infarction in the interventional era: observational case-control study--Japanese acute coronary syndrome study (JACSS)
A retrospective comparison of pregnancy outcomes between women with alpha-thalassaemia 1 trait and normal controls
Incidence and Risks of Congenital Anomalies of Kidney and Urinary Tract in Newborns: A Population-Based Case-Control Study in Taiwan
Experiences of a High-Risk Population with Prenatal Hemoglobinopathy Carrier Screening in a Primary Care Setting: a Qualitative Study
Attitudes of general practitioners and midwives towards ethnicity-based haemoglobinopathy-carrier screening
The Risk of Pregnancy Related Hypertension Disorder Associated with Sickle Cell Trait in U.S. Service Women.
Getting the basic rights - the role of water, sanitation and hygiene in maternal and reproductive health: a conceptual framework
Dengue infection during pregnancy and adverse maternal, fetal, and infant health outcomes in Rio Branco, Acre State, Brazil, 2007-2012
Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.