Maternal and perinatal outcomes and pharmacological management of Covid-19 infection in pregnancy: a systematic review protocol

Systematic Reviews
Binny ThomasMoza Al Hail

Abstract

Over 4.2 million confirmed cases and more than 285,000 deaths, COVID-19 pandemic continues to harm significant number of people worldwide. Several studies have reported the impact of COVID-19 in general population; however, there is scarcity of information related to pharmacological management and maternal and perinatal outcomes during the pandemic. Altered physiological, anatomical, and immunological response during pregnancy makes it more susceptible to infections. Furthermore, during pregnancy, a woman undergoes multiple interactions with the health care system that increases her chance of getting infected; therefore, managing pregnant population presents a unique challenge. This systematic review seeks to answer the following questions in relation to COVID-19: What are the different clinical characteristics presented in maternal and perinatal population? What are the different maternal and perinatal outcome measures reported? What are the distinct therapeutic interventions reported to treat COVID-19? Is it safe to use "medications" used in the treatment of COVID-19 during antenatal, perinatal, postnatal, and breastfeeding? The search will follow a comprehensive, sequential three step search strategy. Several databases relev...Continue Reading

References

Oct 20, 2011·BMJ : British Medical Journal·Julian P T HigginsUNKNOWN Cochrane Statistical Methods Group
Mar 24, 2016·Journal of Clinical Epidemiology·Jessie McGowanCarol Lefebvre
Apr 14, 2016·The New England Journal of Medicine·Sonja A RasmussenLyle R Petersen
Nov 5, 2016·JAMA Pediatrics·Cynthia A MooreSonja A Rasmussen
Feb 9, 2018·BMJ Evidence-based Medicine·Mohammad Hassan MuradFateh Bazerbachi
Feb 29, 2020·The New England Journal of Medicine·Wei-Jie GuanUNKNOWN China Medical Treatment Expert Group for Covid-19
Mar 1, 2020·International Journal of Surgery·Catrin SohrabiRiaz Agha
Mar 3, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Xiaotong WangXinghua Shen
Mar 8, 2020·The Journal of Infection·Yangli LiuYubiao Guo
Mar 11, 2020·Translational Pediatrics·Huaping ZhuWenhao Zhou
Mar 25, 2020·International Journal of Antimicrobial Agents·Philippe GautretDidier Raoult
Apr 14, 2020·Travel Medicine and Infectious Disease·Parisa KaramiAmir Hossein Norooznezhad

❮ Previous
Next ❯

Citations

Nov 23, 2020·Maternal and Child Health Journal·Xue Ling AngJill Cheng Sim Lee
Feb 28, 2021·Journal of Clinical Pharmacy and Therapeutics·Inés Jiménez-LozanoMaria Queralt Gorgas Torner
Oct 13, 2020·Journal of the American College of Clinical Pharmacy : JAACP·Debra A GoffNatalie Schellack

❮ Previous
Next ❯

Methods Mentioned

BETA
cesarean section

Software Mentioned

Cochrane Risk of Bias
RefWorks
PRISMA
NOS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.