Maternal antioxidant provisioning mitigates pollutant-induced oxidative damage in embryos of the temperate sea urchin Evechinus chloroticus

Scientific Reports
Kathryn N ListerDavid J Burritt

Abstract

One mechanism of pollution resistance in marine populations is through transgenerational plasticity, whereby offspring capacity to resist pollution reflects parental exposure history. Our study aimed to establish correlations between oxidative stress biomarkers and key reproductive fitness parameters in the temperate sea urchin Evechinus chloroticus following exposure to dietary polycyclic aromatic hydrocarbons (PAHs). PAH-exposed adults exhibited total gonad tissue concentrations of PAHs in excess of 4 and 5 times baseline levels, for females and males respectively. Antioxidant enzymes were upregulated and oxidative lipid and protein damage to gonad tissues occurred. In addition, early stage offspring reflected maternal antioxidant status, with progeny derived from exposed females demonstrating significantly higher baselines than those derived from control females. Maternal exposure history enhanced the capacity of embryos to minimise oxidative damage to lipids and proteins following exposure to additional PAHs, but provided less of an advantage in protection against oxidative DNA damage. Abnormal embryonic development was largely independent of oxidative damage, remaining high in all embryo populations regardless of parental ...Continue Reading

References

Oct 14, 2003·The Journal of Experimental Biology·Michael P LesserThomas M Barry
Oct 16, 2003·Bulletin of Environmental Contamination and Toxicology·E A AlmeidaP Di Mascio
Nov 18, 2005·Journal of Toxicology and Environmental Health. Part a·Ketil Hylland
Feb 8, 2006·Annual Review of Physiology·Michael P Lesser
Apr 22, 2006·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Eduardo Alves de AlmeidaPaolo Di Mascio
Feb 1, 2007·Proceedings of the National Academy of Sciences of the United States of America·Amro Hamdoun, David Epel
Jan 31, 2008·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·J L Tarry-AdkinsS E Ozanne
Sep 23, 2008·Ecology Letters·David Costantini
Jul 29, 2010·Photochemistry and Photobiology·Kathryn Naomi ListerDavid J Burritt
Mar 15, 2013·Trends in Ecology & Evolution·Neil B Metcalfe, Pat Monaghan
Aug 15, 2013·Marine Environmental Research·Francesco Regoli, Maria Elisa Giuliani
Dec 5, 2013·Environmental Science & Technology·Mary A SewellGretchen E Hofmann
Feb 27, 2016·Scientific Reports·Immacolata CastellanoAnna Palumbo

❮ Previous
Next ❯

Citations

Feb 26, 2020·International Journal of Environmental Research and Public Health·Toshio SekiguchiShuichi Wada
Jan 14, 2021·International Journal of Environmental Research and Public Health·Xuanbo WangDeqi Xiong

❮ Previous
Next ❯

Methods Mentioned

BETA
environmental stress

Software Mentioned

SPSS
SigmaStat
JMP

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.