Maternal autoantibodies and pregnancy--I: The antiphospholipid antibody syndrome

Baillière's Clinical Rheumatology
E N Harris

Abstract

Despite the considerable interest in antiphospholipid antibodies during the last 10 years, the clinical disorders with which they are associated are still not well understood (Love and Santoro, 1990). The concept of the antiphospholipid syndrome (APS) and a means by which this can be defined (Harris, 1987) may aid us in better classifying these patients, evaluating their clinical features, and in conducting prospective studies. Standard methods for measurement of anticardiolipin antibodies (Harris et al, 1987b; Harris and the Kingston Anticardiolipin Standardization Group, 1990) and more attention to measurement of the lupus anticoagulant (Triplett and Brandt, 1988) will ultimately play an important role in improving the diagnosis of these patients. The initiation of the Kingston AntiPhospholipid Study (KAPS) group in January 1988 paves the way for future multicentre treatment trials of these patients (Harris, 1988; Triplett, 1989; Recker and Leff, 1989). For the practising physician managing a pregnant woman with the APS, there are few clear guidelines for treatment. An appropriate approach would be to assemble a multidisciplinary team for pregnancy management, exclude other causes of pregnancy loss and select the drug regimen...Continue Reading

References

Mar 1, 1975·Acta Medica Scandinavica·I M NilssonD Berezin
May 1, 1990·American Journal of Obstetrics and Gynecology·W F Lubbe, N S Pattison
Jan 1, 1990·British Journal of Haematology·E N Harris
Jan 1, 1990·The British Journal of Dermatology·R A Asherson, M A Khamashta
Apr 1, 1990·American Journal of Obstetrics and Gynecology·S Cowchock, D J Balaban
Mar 15, 1989·Annals of Internal Medicine·A ParkeM Ballow
Jun 1, 1989·American Journal of Obstetrics and Gynecology·N GleicherJ Friberg
Jun 1, 1989·American Journal of Reproductive Immunology : AJRI·D A Triplett
Oct 1, 1989·Annals of the Rheumatic Diseases·J OrdiE Genover
Sep 27, 1986·Lancet·C J LockwoodJ C Hobbins
Feb 1, 1989·American Journal of Obstetrics and Gynecology·M D LockshinT Qamar
Sep 1, 1987·Annals of Internal Medicine
Sep 1, 1987·American Journal of Obstetrics and Gynecology·R M Pitkin
Nov 1, 1988·The American Journal of Medicine·E N Harris
Oct 1, 1988·Annals of the Rheumatic Diseases·M A KhamashtaG R Hughes
Dec 1, 1987·American Journal of Obstetrics and Gynecology·P E PattonE Bergstralh
Jun 1, 1986·Clinical Immunology and Immunopathology·J P ClauvelJ C Brouet
Nov 1, 1986·American Journal of Obstetrics and Gynecology·S CowchockB Gocial
Oct 1, 1987·British Journal of Rheumatology·E N Harris
Jan 1, 1987·American Journal of Obstetrics and Gynecology·A M UnanderL Arfors
Nov 21, 1985·The New England Journal of Medicine·D W BranchE Hershgold
Feb 1, 1985·British Journal of Haematology·E N HarrisG R Hughes
Oct 15, 1984·American Journal of Obstetrics and Gynecology·S CowchockL G Jackson
Apr 1, 1984·British Journal of Obstetrics and Gynaecology·W F LubbeG C Liggins
Nov 1, 1984·Clinical and Experimental Dermatology·G R Hughes

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Citations

Oct 17, 1998·American Journal of Surgery·M S al-Hakeem, M A McMillen
Aug 1, 1993·The Australian & New Zealand Journal of Obstetrics & Gynaecology·D N Munday, W R Jones
Jun 1, 1994·The Australian & New Zealand Journal of Obstetrics & Gynaecology·W R Jones
May 1, 1995·The Australian & New Zealand Journal of Obstetrics & Gynaecology·M IlberyJ Sampson
Dec 31, 1998·American Journal of Reproductive Immunology : AJRI·R D FranklinW H Kutteh
Jan 1, 1997·American Journal of Reproductive Immunology : AJRI·R N Taylor
Oct 6, 1998·Scandinavian Journal of Rheumatology. Supplement·E N Harris, S S Pierangeli

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